Eliminated sequences with different copy numbers clustered in the micronuclear genome of Tetrahymena thermophila
dc.contributor.author | Allen, Sally Lyman | en_US |
dc.contributor.author | White, Theodore C. | en_US |
dc.contributor.author | El-Gewely, M. Raafat | en_US |
dc.date.accessioned | 2006-09-11T19:07:28Z | |
dc.date.available | 2006-09-11T19:07:28Z | |
dc.date.issued | 1985-09 | en_US |
dc.identifier.citation | White, Theodore C.; El-Gewely, M. Raafat; Allen, Sally Lyman; (1985). "Eliminated sequences with different copy numbers clustered in the micronuclear genome of Tetrahymena thermophila ." MGG Molecular & General Genetics 201(1): 65-75. <http://hdl.handle.net/2027.42/47561> | en_US |
dc.identifier.issn | 1617-4623 | en_US |
dc.identifier.issn | 0026-3925 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/47561 | |
dc.description.abstract | As the ciliated protozoan Tetrahymena thermophila develops a new macronucleus (MAC) from products of its micronucleus (MIC), several repetitive sequences are eliminated from the MAC genome. Four MIC DNA clones containing repetitive sequences that are eliminated from the MAC were obtained. One clone contains a representative from each of three families of eliminated sequences. One, present in 200–300 copies in the MIC, is almost completely eliminated from the MAC. A second, present in approximately 50 copies in the MIC, is scattered throughout the genome, although up to half of the family members examined could be localized to chromosome 2. Approximately one tenth of the members of this less repetitive family persist in the MAC while the rest are eliminated. The third type of eliminated sequence has three to four members, all of which are eliminated from the MAC. Three of the members are located on three of the five MIC chromosomes, and one could not be mapped. This sequence is clustered with the other two families of sequences in at least three of the four sites. All three types of eliminated sequences are found in similar arrangements in the MIC of several different inbred strains of T. thermophila . | en_US |
dc.format.extent | 1315439 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag | en_US |
dc.subject.other | Cell Biology | en_US |
dc.subject.other | Life Sciences | en_US |
dc.subject.other | Biochemistry, General | en_US |
dc.subject.other | Microbial Genetics and Genomics | en_US |
dc.title | Eliminated sequences with different copy numbers clustered in the micronuclear genome of Tetrahymena thermophila | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Genetics | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Division of Biological Sciences, The University of Michigan, 48109, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Division of Biological Sciences, The University of Michigan, 48109, Ann Arbor, MI, USA; Netherlands Cancer Institute, Plesmanlaan 21, 1066 CX, Amsterdam, The Netherlands | en_US |
dc.contributor.affiliationum | Division of Biological Sciences, The University of Michigan, 48109, Ann Arbor, MI, USA; Department of Biological Chemistry, Medical School, The University of Michigan, 48109, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/47561/1/438_2004_Article_BF00397988.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF00397988 | en_US |
dc.identifier.source | MGG Molecular & General Genetics | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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