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The identification of the B S breakpoint and of two possible Bar genes

dc.contributor.authorTsubota, Stuart I.en_US
dc.contributor.authorSanders, Matthewen_US
dc.contributor.authorNorris, Elizabethen_US
dc.contributor.authorCrumety, Vincenten_US
dc.date.accessioned2006-09-11T19:08:58Z
dc.date.available2006-09-11T19:08:58Z
dc.date.issued1992-05en_US
dc.identifier.citationNorris, Elizabeth; Sanders, Matthew; Crumety, Vincent; Tsubota, Stuart I.; (1992). "The identification of the B S breakpoint and of two possible Bar genes." MGG Molecular & General Genetics 233 (1-2): 106-112. <http://hdl.handle.net/2027.42/47582>en_US
dc.identifier.issn1617-4623en_US
dc.identifier.issn0026-8925en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/47582
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1603054&dopt=citationen_US
dc.description.abstractTwo coding regions were identified within a 110 kb region which includes all mapped Bar breakpoints. Both lie proximal to the identified Bar breakpoints. The first coding region, designated BarA , is 5 kb from the most proximal Bar mutation, B 581 , and 66 kb from the B S breakpoint. It encodes a 1.3 kb transcript, which is found in late third instar larvae but is absent in 1–3-day-old pupae. B i , R(B) hd3 , B 85c1s and B S result in overproduction of this transcript in late third instar larvae. A second coding region, which was previously identified as BarH1 , maps 18 kb from B 581 and 79 kb from the B S breakpoint. In third instar larvae, the abundance of the BarH1 transcript is very low in both wild type and various Bar mutatants, with the exception of R(B) hd3 . In 1–3-day-old pupae, the level of the BarH1 transcript is higher. BarH1 was previously identified as the Bar gene. However, this report raises the possibility that BarA rather than BarH1 is the Bar gene or that more than one gene may be involved in Bar position effects.en_US
dc.format.extent1121156 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherSpringer-Verlagen_US
dc.subject.otherLife Sciencesen_US
dc.subject.otherBarH1en_US
dc.subject.otherBaren_US
dc.subject.otherBarAen_US
dc.subject.otherDrosophila Melanogasteren_US
dc.subject.otherMicrobial Genetics and Genomicsen_US
dc.subject.otherCell Biologyen_US
dc.subject.otherBiochemistry, Generalen_US
dc.subject.otherPosition Effectsen_US
dc.titleThe identification of the B S breakpoint and of two possible Bar genesen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelGeneticsen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Biology, University of Michigan, 48109, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumDepartment of Biology, University of Michigan, 48109, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumDepartment of Biology, University of Michigan, 48109, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumDepartment of Biology, University of Michigan, 48109, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid1603054en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/47582/1/438_2004_Article_BF00587567.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/BF00587567en_US
dc.identifier.sourceMGG Molecular & General Geneticsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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