Genetic studies of the Macushi and Wapishana Indians
dc.contributor.author | Salzano, Francisco M. | en_US |
dc.contributor.author | Migliazza, Ernest C. | en_US |
dc.contributor.author | Neel, James V. | en_US |
dc.contributor.author | Spielman, Richard S. | en_US |
dc.contributor.author | Gershowitz, Henry | en_US |
dc.contributor.author | Oliver, William J. | en_US |
dc.date.accessioned | 2006-09-11T19:10:58Z | |
dc.date.available | 2006-09-11T19:10:58Z | |
dc.date.issued | 1977-01 | en_US |
dc.identifier.citation | Neel, James V.; Gershowitz, Henry; Spielman, Richard S.; Migliazza, Ernest C.; Salzano, Francisco M.; Oliver, William J.; (1977). "Genetic studies of the Macushi and Wapishana Indians." Human Genetics 37(2): 207-219. <http://hdl.handle.net/2027.42/47606> | en_US |
dc.identifier.issn | 1432-1203 | en_US |
dc.identifier.issn | 0340-6717 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/47606 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=407146&dopt=citation | en_US |
dc.description.abstract | Blood samples from 509 Macushi (3 villages) and 623 Wapishana (11 villages) of Northern Brasil and Southern Guyana have been analyzed with respect to the phenotype and gene frequencies at the following 12 polymorphic loci: AB0, Kell-Cellano, MNSs, Rh, P, Duffy, Kidd, Diego, Lewis, Group-specific component, and the immunoglobulin allotypes of the Gm and Inv systems. The data suggest that 5–6% of the Wapishana gene pool is derived from non-Indians but only 1–2% of the Macushi. Inter- and intratribal genetic distances between villages are calculated for these data in an effort to understand gene flow between the tribes and to account for the unusual distribution of a newly-discovered genetic polymorphism of erythrocyte esterase A thus far limited to these 2 tribes (Neel et al., 1977). The data are puzzling and consistent with the possibility that both the Craib-speaking Macushi and the Arawak-speaking Wapishana have derived the esterase A allele in question from some third group now extinct or thus far undiscovered. Intertribal genetic distances based on gene frequencies at 6 loci are derived for 20 Amerindian tribes (including these 2); the “central” position of these 2 tribes can in part be explained by the active migration matrix connecting them. | en_US |
dc.format.extent | 706386 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag | en_US |
dc.subject.other | Molecular Medicine | en_US |
dc.subject.other | Biomedicine | en_US |
dc.subject.other | Human Genetics | en_US |
dc.subject.other | Internal Medicine | en_US |
dc.subject.other | Metabolic Diseases | en_US |
dc.title | Genetic studies of the Macushi and Wapishana Indians | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Genetics | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Human Genetics, University of Michigan Medical School, 48109, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Human Genetics, University of Michigan Medical School, 48109, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Human Genetics, University of Michigan Medical School, 48109, Ann Arbor, Michigan, USA; Department of Human Genetics, University of Pennsylvania School of Medicine, 19 174, Philadelphia, Pennsylvania, USA | en_US |
dc.contributor.affiliationum | Department of Human Genetics, University of Michigan Medical School, 48109, Ann Arbor, Michigan, USA; Department of Anthropology, University of Maryland, 20 742, College Park, Maryland, USA | en_US |
dc.contributor.affiliationum | Department of Pediatrics, University of Michigan School of Medicine, 48 109, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationother | Departamento de Genetica, Universidade de Rio Grande do Sul, Caixa Postal 1953, Porto Alegre, R.G.S., Brasil | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 407146 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/47606/1/439_2004_Article_BF00393584.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF00393584 | en_US |
dc.identifier.source | Human Genetics | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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