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Assignment of the human CRABP-II gene to chromosome 1q21 by nonisotopic in situ hybridization
dc.contributor.authorVoorhees, John J.en_US
dc.contributor.authorPettersson, Ulrikaen_US
dc.contributor.authorÅström, Andersen_US
dc.contributor.authorElder, James T.en_US
dc.contributor.authorTrent, Jeffrey M.en_US
dc.date.accessioned2006-09-11T19:12:44Z
dc.date.available2006-09-11T19:12:44Z
dc.date.issued1992-07en_US
dc.identifier.citationElder, J. T.; Åström, A.; Pettersson, U.; Voorhees, J. J.; Trent, J. M.; (1992). "Assignment of the human CRABP-II gene to chromosome 1q21 by nonisotopic in situ hybridization." Human Genetics 89(5): 487-490. <http://hdl.handle.net/2027.42/47631>en_US
dc.identifier.issn1432-1203en_US
dc.identifier.issn0340-6717en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/47631
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1321791&dopt=citationen_US
dc.description.abstractTwo highly conserved forms of cellular retinoic acid binding protein (CRABP-I and CRABP-II) have been described, and one, CRABP-II, is highly expressed in human skin. We have utilized a 10-kb fragment containing the human CRABP-II (hCRABP-II) gene (isolated from a human genomic library) to localize hCRABP-II to human chromosome 1 band q21 by fluorescence in situ hybridization. Localization to 1q was confirmed by hybridization of a hCRABP-II cDNA clone against a human-mouse hybrid cell line containing a t(1;6)(q21;q13) translocation chromosome. The hCRABP-II gene is therefore localized to a band known to contain several other genes that are expressed in the context of epidermal differentiation, including profilaggrin, loricrin, involucrin, and calcyclin.en_US
dc.format.extent494290 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherSpringer-Verlagen_US
dc.subject.otherBiomedicineen_US
dc.subject.otherHuman Geneticsen_US
dc.subject.otherInternal Medicineen_US
dc.subject.otherMetabolic Diseasesen_US
dc.subject.otherMolecular Medicineen_US
dc.titleAssignment of the human CRABP-II gene to chromosome 1q21 by nonisotopic in situ hybridizationen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelGeneticsen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Dermatology, The University of Michigan Medical School, 1150 West Medical Center Drive, 48109-0668, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumDepartment of Dermatology, The University of Michigan Medical School, 1150 West Medical Center Drive, 48109-0668, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumDepartment of Dermatology, The University of Michigan Medical School, 1150 West Medical Center Drive, 48109-0668, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumDepartment of Dermatology, The University of Michigan Medical School, 1150 West Medical Center Drive, 48109-0668, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumDepartment of Radiation Oncology and Human Genetics, The University of Michigan Medical School, 1150 West Medical Center Drive, 48109-0668, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid1321791en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/47631/1/439_2004_Article_BF00219171.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/BF00219171en_US
dc.identifier.sourceHuman Geneticsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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