Evaluation of the effects of sensory denervation on osteoblasts by 3 H-proline autoradiography
dc.contributor.author | Chiego, Daniel J. | en_US |
dc.contributor.author | Singh, I. J. | en_US |
dc.date.accessioned | 2006-09-11T19:15:47Z | |
dc.date.available | 2006-09-11T19:15:47Z | |
dc.date.issued | 1981-06 | en_US |
dc.identifier.citation | Chiego, D. J.; Singh, I. J.; (1981). "Evaluation of the effects of sensory denervation on osteoblasts by 3 H-proline autoradiography." Cell and Tissue Research 217(3): 569-576. <http://hdl.handle.net/2027.42/47675> | en_US |
dc.identifier.issn | 0302-766X | en_US |
dc.identifier.issn | 1432-0878 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/47675 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7249051&dopt=citation | en_US |
dc.description.abstract | The inferior alveolar nerve was unilaterally resected in 30-day-old mice; other animals were unilaterally sham-operated. At 15, 30, 60, 90, or 150 days after surgery, the mice were injected with 2μCi of 3 H-proline (sp. act. 1.0 Ci/mM) per g of body weight and killed 15, 30, or 60 min later. Autoradiographs were prepared from 5μm decalcified sagittal sections of mandibles and grain counts made over periosteal osteoblasts mesial to the first molar. In denervated mandibles, osteoblasts incorporated less isotope compared to controls with differences being maximal at the early intervals. These differences became attenuated with time, possibly due to an intrinsic compensatory mechanism, secondary to neurotrophic regulation. | en_US |
dc.format.extent | 870239 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag | en_US |
dc.subject.other | Denervation | en_US |
dc.subject.other | Osteoblasts | en_US |
dc.subject.other | 3 H-proline | en_US |
dc.subject.other | Autoradiography | en_US |
dc.subject.other | Biomedicine | en_US |
dc.subject.other | Cell Biology | en_US |
dc.subject.other | Neurosciences | en_US |
dc.subject.other | Neurology | en_US |
dc.subject.other | Endocrinology | en_US |
dc.title | Evaluation of the effects of sensory denervation on osteoblasts by 3 H-proline autoradiography | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Anatomy, New York University Dental Center, New York, N.Y., USA; Dental Research Institute, University of Michigan, School of Dentistry, 48109, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationother | Department of Anatomy, New York University Dental Center, New York, N.Y., USA; Department of Anatomy, New York University Dental Center, 345 E. 24th Street, 10010, New York, N.Y., USA | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 7249051 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/47675/1/441_2004_Article_BF00219365.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF00219365 | en_US |
dc.identifier.source | Cell and Tissue Research | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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