Autoradiographic evidence that transport of newly synthesized neuropeptides is directed to release sites in the X-organsinus gland of Cardisoma carnifex
dc.contributor.author | Stuenkel, Edward L. | en_US |
dc.contributor.author | Cooke, I. | en_US |
dc.contributor.author | Gillary, E. | en_US |
dc.date.accessioned | 2006-09-11T19:16:44Z | |
dc.date.available | 2006-09-11T19:16:44Z | |
dc.date.issued | 1991-05 | en_US |
dc.identifier.citation | Stuenkel, E.; Gillary, E.; Cooke, I.; (1991). "Autoradiographic evidence that transport of newly synthesized neuropeptides is directed to release sites in the X-organsinus gland of Cardisoma carnifex ." Cell and Tissue Research 264(2): 253-262. <http://hdl.handle.net/2027.42/47688> | en_US |
dc.identifier.issn | 0302-766X | en_US |
dc.identifier.issn | 1432-0878 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/47688 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1878945&dopt=citation | en_US |
dc.description.abstract | Sections of isolated X-organ — sinus gland neurosecretory systems of the crab, Cardisoma carnifex , were studied by light-and electron microscopy with conventional and autoradiographic procedures. The somata only were exposed to a pulse of 3 H-leucine (5 min-5 h) and the entire system perfused with chase medium for various times (1–72 h) before fixation. Within 1 h, radiolabel is concentrated in Golgi complexes and nascent granules of both large and small somata. Label is undetectable in the terminal region following a 10 h chase. It is found in the nerve tract near terminals at 14 h, while after a 19 h chase, label is concentrated in terminal profiles abutting blood sinuses of the neurohemal organ (sinus gland). Following a 72 h chase, label is distributed throughout the terminal region. Each of the six morphologically distinguishable terminal types shows labelling. These observations show that the vast majority of newly formed granules are initially transported to release sites of the perisinus terminals. They thus provide an explanation for previous analyses indicating that newly synthesized peptides are preferentially secreted. | en_US |
dc.format.extent | 6112528 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag | en_US |
dc.subject.other | Cardisoma Carnifex (Crustacea) | en_US |
dc.subject.other | Peptidergic Neurons | en_US |
dc.subject.other | Axonal Transport | en_US |
dc.subject.other | Crustacea | en_US |
dc.subject.other | Endocrinology | en_US |
dc.subject.other | Neurosciences | en_US |
dc.subject.other | Cell Biology | en_US |
dc.subject.other | Neurology | en_US |
dc.subject.other | Neurosecretion | en_US |
dc.subject.other | Biomedicine | en_US |
dc.subject.other | Neuronemal Organ | en_US |
dc.title | Autoradiographic evidence that transport of newly synthesized neuropeptides is directed to release sites in the X-organsinus gland of Cardisoma carnifex | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Physiology, University of Michigan, 48109, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationother | Bekesy Laboratory of Neurobiology and Department of Zoology, University of Hawaii, 1993 East-West Road, 96822, Honolulu, HI, USA | en_US |
dc.contributor.affiliationother | Bekesy Laboratory of Neurobiology and Department of Zoology, University of Hawaii, 1993 East-West Road, 96822, Honolulu, HI, USA | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 1878945 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/47688/1/441_2004_Article_BF00313962.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF00313962 | en_US |
dc.identifier.source | Cell and Tissue Research | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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