Nucleotide sequence comparison of the Adh gene in three drosophilids
dc.contributor.author | Moore, Gordon P. | en_US |
dc.contributor.author | Cohn, Vivian H. | en_US |
dc.contributor.author | Thompson, Margaret A. | en_US |
dc.date.accessioned | 2006-09-11T19:41:22Z | |
dc.date.available | 2006-09-11T19:41:22Z | |
dc.date.issued | 1984-02 | en_US |
dc.identifier.citation | Cohn, Vivian H.; Thompson, Margaret A.; Moore, Gordon P.; (1984). "Nucleotide sequence comparison of the Adh gene in three drosophilids." Journal of Molecular Evolution 20(1): 31-37. <http://hdl.handle.net/2027.42/48039> | en_US |
dc.identifier.issn | 1432-1432 | en_US |
dc.identifier.issn | 0022-2844 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/48039 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6429340&dopt=citation | en_US |
dc.description.abstract | The alcohol dehydrogenase (Adh) gene has been isolated from Drosophila simulans and D. mauritiana by screening λ clone libraries of each with a previously cloned Adh gene from D. melanogaster . The isolated λ clones were subcloned and partially sequenced to determine the relatedness of these species and to examine details of evolutionary change in the structure of the Adh gene. We report the sequence of the first 704 nucleotides of each gene as well as 127 bases in the 5′ untranslated region. When these sequences are compared, D. melanogaster differs from D. simulans and D. mauritiana by 2.8% and 3.1%, respectively. D. simulans and D. mauritiana differ by only 1.8%, implying that they are more closely related to each other than either is to D. melanogaster . This is consistent with phylogenetic relationships established by a variety of genetic, biochemical, and morphological means and illustrates that DNA sequencing of a single gene may be used to assess the evolutionary relationships of species. | en_US |
dc.format.extent | 668851 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag | en_US |
dc.subject.other | Life Sciences | en_US |
dc.subject.other | Plant Sciences | en_US |
dc.subject.other | Alcohol Dehydrogenase | en_US |
dc.subject.other | Cell Biology | en_US |
dc.subject.other | Microbiology | en_US |
dc.subject.other | DNA Sequence | en_US |
dc.subject.other | Drosophilids | en_US |
dc.title | Nucleotide sequence comparison of the Adh gene in three drosophilids | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Division of Biological Sciences, University of Michigan, 48109, Ann Arbor, Michigan, USA; The Biological Laboratories, Harvard University, 02138, Cambridge, Massachusetts, USA | en_US |
dc.contributor.affiliationum | Division of Biological Sciences, University of Michigan, 48109, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Division of Biological Sciences, University of Michigan, 48109, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 6429340 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/48039/1/239_2005_Article_BF02101983.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF02101983 | en_US |
dc.identifier.source | Journal of Molecular Evolution | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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