Show simple item record

Nucleotide sequence comparison of the Adh gene in three drosophilids

dc.contributor.authorMoore, Gordon P.en_US
dc.contributor.authorCohn, Vivian H.en_US
dc.contributor.authorThompson, Margaret A.en_US
dc.date.accessioned2006-09-11T19:41:22Z
dc.date.available2006-09-11T19:41:22Z
dc.date.issued1984-02en_US
dc.identifier.citationCohn, Vivian H.; Thompson, Margaret A.; Moore, Gordon P.; (1984). "Nucleotide sequence comparison of the Adh gene in three drosophilids." Journal of Molecular Evolution 20(1): 31-37. <http://hdl.handle.net/2027.42/48039>en_US
dc.identifier.issn1432-1432en_US
dc.identifier.issn0022-2844en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/48039
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6429340&dopt=citationen_US
dc.description.abstractThe alcohol dehydrogenase (Adh) gene has been isolated from Drosophila simulans and D. mauritiana by screening λ clone libraries of each with a previously cloned Adh gene from D. melanogaster . The isolated λ clones were subcloned and partially sequenced to determine the relatedness of these species and to examine details of evolutionary change in the structure of the Adh gene. We report the sequence of the first 704 nucleotides of each gene as well as 127 bases in the 5′ untranslated region. When these sequences are compared, D. melanogaster differs from D. simulans and D. mauritiana by 2.8% and 3.1%, respectively. D. simulans and D. mauritiana differ by only 1.8%, implying that they are more closely related to each other than either is to D. melanogaster . This is consistent with phylogenetic relationships established by a variety of genetic, biochemical, and morphological means and illustrates that DNA sequencing of a single gene may be used to assess the evolutionary relationships of species.en_US
dc.format.extent668851 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherSpringer-Verlagen_US
dc.subject.otherLife Sciencesen_US
dc.subject.otherPlant Sciencesen_US
dc.subject.otherAlcohol Dehydrogenaseen_US
dc.subject.otherCell Biologyen_US
dc.subject.otherMicrobiologyen_US
dc.subject.otherDNA Sequenceen_US
dc.subject.otherDrosophilidsen_US
dc.titleNucleotide sequence comparison of the Adh gene in three drosophilidsen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDivision of Biological Sciences, University of Michigan, 48109, Ann Arbor, Michigan, USA; The Biological Laboratories, Harvard University, 02138, Cambridge, Massachusetts, USAen_US
dc.contributor.affiliationumDivision of Biological Sciences, University of Michigan, 48109, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDivision of Biological Sciences, University of Michigan, 48109, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid6429340en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/48039/1/239_2005_Article_BF02101983.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/BF02101983en_US
dc.identifier.sourceJournal of Molecular Evolutionen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Show simple item record