Evolution of two actin genes in the sea urchin Strongylocentrotus franciscanus

Moore, Gordon P.; Foran, David R.; Johnson, Patricia J.

Moore, Gordon P.; Foran, David R.; Johnson, Patricia J.

1985-10

Citation: Foran, David R.; Johnson, Patricia J.; Moore, Gordon P.; (1985). "Evolution of two actin genes in the sea urchin Strongylocentrotus franciscanus ." Journal of Molecular Evolution 22(2): 108-116. <http://hdl.handle.net/2027.42/48040>

Abstract: The complete nucleotide sequences of two chromosomally linked actin genes from the sea urchin Strongylocentrotus franciscanus are presented. The genes are separated by 5.7 kilobases, occur in the same transcriptional orientation, and contain introns in identical positions. The structures and nucleotide sequences of the two genes are extremely similar, suggesting that they arose through a recent duplication. Comparison of the nucleotide sequences of the genes allows inferences to be made about mutational mechanisms active since the duplication event. Whereas point mutations predominate in the coding regions, the introns and flanking DNA are more heavily influenced by a variety of events that cause simultaneous changes in short regions of DNA.

ISSN: 1432-1432, 0022-2844

Other DOI(s):
http://dx.doi.org/10.1007/BF02101689

PMID: 2999411

Handle:
http://hdl.handle.net/2027.42/48040

URI:
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2999411&dopt=citation

Type(s): Article

Show full item record

Accessibility: If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.