Surface-modified polyolefin microfluidic devices for liquid handling

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dc.contributor.author Lin, Rongsheng en_US
dc.contributor.author Burns, Mark A. en_US
dc.date.accessioned 2006-12-19T19:09:08Z
dc.date.available 2006-12-19T19:09:08Z
dc.date.issued 2005-11-01 en_US
dc.identifier.citation Lin, Rongsheng; Burns, Mark A (2005). "Surface-modified polyolefin microfluidic devices for liquid handling." Journal of Micromechanics and Microengineering. 15(11): 2156-2162. <http://hdl.handle.net/2027.42/49036> en_US
dc.identifier.issn 0960-1317 en_US
dc.identifier.uri http://hdl.handle.net/2027.42/49036
dc.description.abstract Polymer-based microfluidic devices offer an attractive platform for single-use disposable applications due to their low cost, ease of fabrication and good biocompatibility. In this work, we investigated liquid handling in surface modified polyolefin microfluidic devices. The modification of the surface was accomplished using ultraviolet light, and the contact angle was reduced from 88° to 45°. This type of treatment is easy to implement and could be beneficial for liquid handling in microchannel networks. Capillary-driven flow, contact angle hysteresis and pulsed pumping were demonstrated in these plastic devices. This surface treatment also facilitates rapid gel loading for separation since viscous sieving media can be injected solely by capillary force. Nucleic acid separation was demonstrated in the gel-loaded devices. en_US
dc.format.extent 3118 bytes
dc.format.extent 465392 bytes
dc.format.mimetype text/plain
dc.format.mimetype application/pdf
dc.language.iso en_US
dc.publisher IOP Publishing Ltd en_US
dc.title Surface-modified polyolefin microfluidic devices for liquid handling en_US
dc.type Article en_US
dc.subject.hlbsecondlevel Physics en_US
dc.subject.hlbtoplevel Science en_US
dc.description.peerreviewed Peer Reviewed en_US
dc.contributor.affiliationum Department of Chemical Engineering, The University of Michigan, Ann Arbor, MI 48109-2136, USA; Department of Electrical Engineering, The University of Michigan, Ann Arbor, MI 48109-2136, USA en_US
dc.contributor.affiliationum Department of Chemical Engineering, The University of Michigan, Ann Arbor, MI 48109-2136, USA; Department of Biomedical Engineering, The University of Michigan, Ann Arbor, MI 48109-2136, USA en_US
dc.contributor.affiliationumcampus Ann Arbor en_US
dc.description.bitstreamurl http://deepblue.lib.umich.edu/bitstream/2027.42/49036/2/jmm5_11_023.pdf en_US
dc.identifier.doi http://dx.doi.org/10.1088/0960-1317/15/11/023 en_US
dc.identifier.source Journal of Micromechanics and Microengineering. en_US
dc.owningcollname Interdisciplinary and Peer-Reviewed
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