Pulsatile luteinizing hormone disruption in depression
Grambsch, Patricia; Young, Elizabeth A.; Meller, William H.
2004
Citation
Psychoneuroendocrinology 29:825-829, 2004 <http://hdl.handle.net/2027.42/49487>
Abstract
Two independent groups recently published data comparing pulsatile luteinizing hormone (LH) release between depressed and control women. Despite similar populations and LH sampling frequency, they reached different conclusions: Meller et al. [Am. J. Psych. 154 (1997) 1454] found disruption of normal LH pulsatility in depressed women, whereas Young et al. [Arch. Gen. Psych. 57 (2000) 1157] did not. To resolve this discrepancy, the current study applies a single, well-established statistical method, spectral analysis, to the two data sets and concludes that both depressed populations display significantly altered LH pulsatile release.Publisher
Elsevier
PMID
15177697
Subjects
Hypothalamo-pituitary-Ovarin Axis Depression
Types
Article
URI
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=15177697&dopt=citationMetadata
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