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The effects of hypophysectomy on the digestive glands of the mouse Supported in part by research grant AM 00131–14 from the United States Public Health Service.

dc.contributor.authorKoerker, Richard Mortsonen_US
dc.date.accessioned2007-04-06T17:40:48Z
dc.date.available2007-04-06T17:40:48Z
dc.date.issued1967-11en_US
dc.identifier.citationKoerker, Richard Mortson (1967)."The effects of hypophysectomy on the digestive glands of the mouse Supported in part by research grant AM 00131–14 from the United States Public Health Service. ." American Journal of Anatomy 121(3): 571-599. <http://hdl.handle.net/2027.42/49645>en_US
dc.identifier.issn0002-9106en_US
dc.identifier.issn1553-0795en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/49645
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=4230254&dopt=citationen_US
dc.description.abstractThe objective was to observe the influence of hypophysectomy on the secretory cells of digestive glands in the mouse and to compare these findings with those reported for other mammalian species. Hypophysectomy of the mouse induced involutional changes in glandular cells concerned with secretion of proteins and mucins, and in those involved in ion transport or release. Gastric chief cells, pancreatic acinar cells, and serous cells of submandibular tubules were markedly involuted; acinar cells of the parotid gland were changed less significantly. Gastric mucous neck cells and mucous acinar cells of the submandibular and sublingual glands contained less secretory material. A colloidal iron-positive variety of mucous neck cell became dominant. These changes were less profound than those which occurred in most types of zymogenic cells. Parietal cells became atrophic and contained a greatly contracted intracellular canalicular system. Salivary ducts of the parotid and sublingual glands showed partial involution. It was concluded that, as in the rat and man, protein-secreting cells of the digestive tract of the mouse depend on the support of pituitary hormones. Those cells which secrete mucopolysaccharides or are involved in ion transport also require pituitary hormones for complete maintenance of their structure and function.en_US
dc.format.extent7572376 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWiley Subscription Services, Inc., A Wiley Companyen_US
dc.subject.otherLife and Medical Sciencesen_US
dc.subject.otherCell & Developmental Biologyen_US
dc.titleThe effects of hypophysectomy on the digestive glands of the mouse Supported in part by research grant AM 00131–14 from the United States Public Health Service.en_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMedicine (General)en_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Anatomy, The University of Michigan Medical School, Ann Arbor, Michigan ; From a dissertation submitted in partial fulfillment of the requirements for the Doctor of Philosophy degree.en_US
dc.identifier.pmid4230254en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/49645/1/1001210309_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/aja.1001210309en_US
dc.identifier.sourceAmerican Journal of Anatomyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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