The role of the convoluted segment of the proximal tubule in the disposal of 131 I-insulin in the rat kidney
dc.contributor.author | Sottiurai, Vikrom | en_US |
dc.date.accessioned | 2007-04-06T17:43:23Z | |
dc.date.available | 2007-04-06T17:43:23Z | |
dc.date.issued | 1974-06 | en_US |
dc.identifier.citation | Sottiurai, Vikrom (1974)."The role of the convoluted segment of the proximal tubule in the disposal of 131 I-insulin in the rat kidney." American Journal of Anatomy 140(2): 181-190. <http://hdl.handle.net/2027.42/49671> | en_US |
dc.identifier.issn | 0002-9106 | en_US |
dc.identifier.issn | 1553-0795 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/49671 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=4826243&dopt=citation | en_US |
dc.description.abstract | It is generally accepted that in the kidney insulin is metabolized in the proximal tubule, but whether in the convoluted segment, the straight segment, or both has not been established. By means of autoradiography counting of radioactivity, and interrupted flow techniques, the following observations have been made. 131 I-labelled porcine insulin is metabolized exclusively in the convoluted segment of the proximal tubule. Although the glomerular filtrate is the major source of insulin supply to the renal epithelia, the peritubular capillary plexuses provide as much as 30% or more of the total insulin delivered to the renal epithelia. The epithelium of the convoluted segment is capable of sequestering 131 I-insulin from the peritubular capillary plexuses, a phenomenon which has not been established previously. | en_US |
dc.format.extent | 676988 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Cell & Developmental Biology | en_US |
dc.title | The role of the convoluted segment of the proximal tubule in the disposal of 131 I-insulin in the rat kidney | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Medicine (General) | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Anatomy, University of Michigan, Medical School, Ann Arbor, Michigan 48104 | en_US |
dc.identifier.pmid | 4826243 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/49671/1/1001400205_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/aja.1001400205 | en_US |
dc.identifier.source | American Journal of Anatomy | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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