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Revascularization of the freely grafted extensor digitorum longus muscle in the rat

dc.contributor.authorHansen-Smith, Fay M.en_US
dc.contributor.authorCarlson, Bruce M.en_US
dc.contributor.authorIrwin, K. L.en_US
dc.date.accessioned2007-04-06T17:44:29Z
dc.date.available2007-04-06T17:44:29Z
dc.date.issued1980-05en_US
dc.identifier.citationHansen-Smith, F. M.; Carlson, B. M.; Irwin, K. L. (1980)."Revascularization of the freely grafted extensor digitorum longus muscle in the rat." American Journal of Anatomy 158(1): 65-82. <http://hdl.handle.net/2027.42/49682>en_US
dc.identifier.issn0002-9106en_US
dc.identifier.issn1553-0795en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/49682
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7416047&dopt=citationen_US
dc.description.abstractThe process of revascularization of free grafts of the extensor digitorum longus muscle in rats has been studied by gross, histological and electron microscopic methods. During the first day after transplantation the muscle is entirely avascular, and it consists of a thin peripheral zone of surviving muscle fibers and a large central area of ischemic muscle. The original blood vessels of the graft undergo a sequence of intrinsic and cell-mediated destruction. Scattered sinusoidal vessels begin to grow into the graft starting on the second day, and ingrowing blood vessels progressively invade the deeper tissues of the graft. Most new vessels form in the connective tissues, but some vessels, especially larger ones, grow into persisting basal laminae from preexisting vessels and, occasionally, even into basal laminae from degenerated muscle fibers and nerves. The differentiation of new arterioles and venules in free muscle grafts is described. By the end of the first week, the entire graft is revascularized, and ultimately a fairly normal relationship between new capillaries and regenerating muscle fibers is established. In mature grafts, however, irregularities are sometimes found in the organization of smooth muscle cells associated with larger vessels.en_US
dc.format.extent2014072 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWiley Subscription Services, Inc., A Wiley Companyen_US
dc.subject.otherLife and Medical Sciencesen_US
dc.subject.otherCell & Developmental Biologyen_US
dc.titleRevascularization of the freely grafted extensor digitorum longus muscle in the raten_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMedicine (General)en_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Anatomy, University of Michigan, Ann Arbor, Michigan 48109en_US
dc.contributor.affiliationumDepartment of Anatomy, University of Michigan, Ann Arbor, Michigan 48109 ; Department of Anatomy, University of Michigan, Ann Arbor, Michigan 48109en_US
dc.contributor.affiliationumDepartment of Anatomy, University of Michigan, Ann Arbor, Michigan 48109en_US
dc.identifier.pmid7416047en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/49682/1/1001580107_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/aja.1001580107en_US
dc.identifier.sourceAmerican Journal of Anatomyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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