Survival of myogenic cells in freely grafted rat rectus femoris and extensor digitorum longus muscles
dc.contributor.author | Phillips, Gregg D. | en_US |
dc.contributor.author | Lu, Danyun | en_US |
dc.contributor.author | Mitashov, Victor I. | en_US |
dc.contributor.author | Carlson, Bruce M. | en_US |
dc.date.accessioned | 2007-04-06T17:45:35Z | |
dc.date.available | 2007-04-06T17:45:35Z | |
dc.date.issued | 1987-12 | en_US |
dc.identifier.citation | Phillips, Gregg D.; Lu, Danyun; Mitashov, Victor I.; Carlson, Bruce M. (1987)."Survival of myogenic cells in freely grafted rat rectus femoris and extensor digitorum longus muscles." American Journal of Anatomy 180(4): 365-372. <http://hdl.handle.net/2027.42/49693> | en_US |
dc.identifier.issn | 0002-9106 | en_US |
dc.identifier.issn | 1553-0795 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/49693 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3425564&dopt=citation | en_US |
dc.description.abstract | The objective of this study was to determine how long myogenic cells can survive in the central ischemic zone of early free muscle grafts in the rat. The study was conducted on free grafts of a large (rectus femoris) and a small (extensor digitorum lon-gus) muscle. At times ranging from zero hr to five days post-grafting, the central zones were isolated, minced, and implanted under the back skin of mice. After five days the minces were removed and examined histologically for the presence of rat myotubes, which should form only in minces that contain viable myogenic cells. The results show that myogenic cells survive two to four hr in the ischemic centers of the large rectus femoris grafts; after longer post-grafting intervals, rat myotubes did not arise in central zone minces. In grafts of small muscles, myotubes consistently appeared in central zone minces. Since the formerly ischemic central areas of rectus muscle grafts are ultimately replaced by regenerating muscle fibers, we conclude that these regenerating muscle fibers are derived from precursor cells located outside of the ischemic zone. | en_US |
dc.format.extent | 1370340 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Cell & Developmental Biology | en_US |
dc.title | Survival of myogenic cells in freely grafted rat rectus femoris and extensor digitorum longus muscles | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Medicine (General) | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Anatomy and Cell Biology, University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.contributor.affiliationum | Department of Anatomy and Cell Biology, University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.contributor.affiliationum | Department of Anatomy and Cell Biology, University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.contributor.affiliationum | Department of Anatomy and Cell Biology, University of Michigan, Ann Arbor, Michigan 48109 ; Department of Biological Sciences, University of Michigan, Ann Arbor, Michigan 48109 ; University of Michigan, Department of Anatomy and Cell Biology, Ann Arbor, Michigan 48109 | en_US |
dc.identifier.pmid | 3425564 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/49693/1/1001800407_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/aja.1001800407 | en_US |
dc.identifier.source | American Journal of Anatomy | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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