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The fine structure of differentiating fibroblasts in the incisor pulp of the guinea pig Supported in part by grant D-1620 from The United States Public Health Service.

dc.contributor.authorHan, Seong Sooen_US
dc.contributor.authorAvery, James K.en_US
dc.contributor.authorHale, Lawrence E.en_US
dc.date.accessioned2007-04-06T17:56:39Z
dc.date.available2007-04-06T17:56:39Z
dc.date.issued1965-10en_US
dc.identifier.citationHan, Seong S.; Avery, James K.; Hale, Lawrence E. (1965)."The fine structure of differentiating fibroblasts in the incisor pulp of the guinea pig Supported in part by grant D-1620 from The United States Public Health Service. ." The Anatomical Record 153(2): 187-209. <http://hdl.handle.net/2027.42/49804>en_US
dc.identifier.issn0003-276Xen_US
dc.identifier.issn1097-0185en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/49804
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=5867112&dopt=citationen_US
dc.description.abstractThe differentiation of the fibroblast was followed in the dental pulp of continuously growing incisors of the guinea pig. Based on the ultrastructure, the processes of differentiation of the fibroblasts might be conveniently broken into three stages; Stage I – period of early differentiation, Stage II – period of maturation and functioning, and Stage III – period of regression. During Stage I the cell had structural characteristics shared by other less differentiated cells. The endoplasmic reticulum was poorly developed, showing vesicular to tubular profiles. The ribosomes were abundant but were mostly distributed in free form. Mitochondria were small and had irregular interiors. Stage II was characterized by a striking development of the rough-surfaced endoplasmic reticulum, which appeared in various shapes and sizes. The Golgi complex was enlarged, and contained some fibriller materials in dilated portions of its membraneous elements. Other features described in the cytoplasm of fibroblasts from other sources were confirmed. Stage III was characterized by the decrease in size and number of various cytoplasmic constituents and was considered to represent cells in the state of regression.en_US
dc.format.extent6697119 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWiley Subscription Services, Inc., A Wiley Companyen_US
dc.subject.otherLife and Medical Sciencesen_US
dc.subject.otherCell & Developmental Biologyen_US
dc.titleThe fine structure of differentiating fibroblasts in the incisor pulp of the guinea pig Supported in part by grant D-1620 from The United States Public Health Service.en_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumThe University of Michigan School of Dentistry and Department of Anatomy, Ann Arbor, Michiganen_US
dc.contributor.affiliationumThe University of Michigan School of Dentistry and Department of Anatomy, Ann Arbor, Michiganen_US
dc.contributor.affiliationumThe University of Michigan School of Dentistry and Department of Anatomy, Ann Arbor, Michiganen_US
dc.identifier.pmid5867112en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/49804/1/1091530208_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/ar.1091530208en_US
dc.identifier.sourceThe Anatomical Recorden_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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