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Diameter and length changes in cerebral collaterals after middle cerebral artery occlusion in the young rat

dc.contributor.authorCoyle, Peteren_US
dc.date.accessioned2007-04-06T18:00:50Z
dc.date.available2007-04-06T18:00:50Z
dc.date.issued1984-10en_US
dc.identifier.citationCoyle, Peter (1984)."Diameter and length changes in cerebral collaterals after middle cerebral artery occlusion in the young rat." The Anatomical Record 210(2): 357-364. <http://hdl.handle.net/2027.42/49846>en_US
dc.identifier.issn0003-276Xen_US
dc.identifier.issn1097-0185en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/49846
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6507901&dopt=citationen_US
dc.description.abstractRapid occlusion of the middle cerebral artery (MCA) in the 36-day-old normal Wistar rat results in change of the dorsal collaterals joining branches of the anterior and middle cerebral arteries. As compared to similarly positioned vessels on the opposite hemisphere and arterioles in unoperated rats of 56 days, of age, there were significantly (P < 0.001) more large (60–120 Μm)diameter collaterals on the occluded side 20 days after MCA occlusion. There were fewer small (0-59Μm) diameter collaterals on the occluded side as compared to unoperated rats. The data suggest small diameter arterioles existing at occlusion became large diameter collaterals. The mean number of collaterals per hemisphere was not significantly different (P > 0.05) between occluded and unoperated rats. There was no evidence that new vessels were added during the 20-day ligation period. The mean collateral tortuosity value was significantly (P < 0.01) greater for large diameter vessels on the right occluded side as compared to vessels on the left hemisphere or vessels in unoperated age-matched control rats. The greater tortuosity values of vessels on the occluded side were evidence that collateral vessel length was increased by 24–29% after MCA occlusion. Speculation was made about possible mechanisms responsible for these vascular changes.en_US
dc.format.extent1512754 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWiley Subscription Services, Inc., A Wiley Companyen_US
dc.subject.otherLife and Medical Sciencesen_US
dc.subject.otherCell & Developmental Biologyen_US
dc.titleDiameter and length changes in cerebral collaterals after middle cerebral artery occlusion in the young raten_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Anatomy and Cell Biology, The University of Michigan Medical School, Ann Arbor, MI 48109en_US
dc.identifier.pmid6507901en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/49846/1/1092100211_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/ar.1092100211en_US
dc.identifier.sourceThe Anatomical Recorden_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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