Taste fiber responses during reinnervation of fungiform papillae
dc.contributor.author | Cheal, Marylou | en_US |
dc.contributor.author | Dickey, William P. | en_US |
dc.contributor.author | Jones, Lee B. | en_US |
dc.contributor.author | Oakley, Bruce | en_US |
dc.date.accessioned | 2007-04-06T18:16:30Z | |
dc.date.available | 2007-04-06T18:16:30Z | |
dc.date.issued | 1977-04-15 | en_US |
dc.identifier.citation | Cheal, Marylou; Dickey, William P.; Jones, Lef B.; Oakley, Bruce (1977)."Taste fiber responses during reinnervation of fungiform papillae." The Journal of Comparative Neurology 172(4): 627-646. <http://hdl.handle.net/2027.42/49998> | en_US |
dc.identifier.issn | 0021-9967 | en_US |
dc.identifier.issn | 1096-9861 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/49998 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=838893&dopt=citation | en_US |
dc.description.abstract | Crushing or transecting the chorda tympani nerve of the gerbil ( Meriones unguiculatus ) caused ipsilateral degeneration of taste buds in the fungiform papillae. In less than two weeks some taste fibers regenerated into the tongue and formed new taste buds and receptor cells. The recovery process was evaluated electrophysiologically in 53 gerbils by acute recording proximal to the nerve injury site. Initially the chorda tympani was electrically silent. In gerbils tested at later times spontaneous activity appeared. This was followed by responses to pressure on the tongue. Taste responses returned as early as dasy 11. The receptive field of regenerated taste fibers was limited to a small number of fungiform papillae. Taste responses were always associasted with the presence of one or more taste buds in the receptive field. Taste buds identified as responsive to chemicals contained some fusiform cells. We found thast the taste responses of single fiber, few-fiber and multi-unit preparations reflected the diversity of responses found in normal taste axons as determined by recording from 26 normal single fibers and 27 normal whole nerves. The early emergence of a variety of fiber types and responses to many chemicals in regeneration is inconsistent with the proposition that the relative chemical responsiveness of a receptor cell is strictly a function of its age; the response of a given young taste receptor is not necessarily limited to a few of the standard taste stimulants. | en_US |
dc.format.extent | 2186126 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Neuroscience, Neurology and Psychiatry | en_US |
dc.title | Taste fiber responses during reinnervation of fungiform papillae | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Division of Biological Sciences, The University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.contributor.affiliationum | Division of Biological Sciences, The University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.contributor.affiliationum | Division of Biological Sciences, The University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.contributor.affiliationum | Division of Biological Sciences, The University of Michigan, Ann Arbor, Michigan 48109 ; Division of Biological Sciences, The University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.identifier.pmid | 838893 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/49998/1/901720406_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/cne.901720406 | en_US |
dc.identifier.source | The Journal of Comparative Neurology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.