Show simple item record

dc.contributor.authorJohns, Pamela Raymonden_US
dc.date.accessioned2007-04-06T18:16:54Z
dc.date.available2007-04-06T18:16:54Z
dc.date.issued1977-12-01en_US
dc.identifier.citationJohns, Pamela Raymond (1977)."Growth of the adult goldfish eye. III. Source of the new retinal cells." The Journal of Comparative Neurology 176(3): 343-357. <http://hdl.handle.net/2027.42/50002>en_US
dc.identifier.issn0021-9967en_US
dc.identifier.issn1096-9861en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/50002
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=915042&dopt=citationen_US
dc.description.abstractThe manner in which new cells are added to the growing adult goldfish retina was examined using 3 H-thymidine radioutography. Cell proliferation leading to the formation of neurons is restricted to the retinal margin at the ora terminalis . New retina is added in concentric rings, with slightly more growth dorsonasally. The rate of cell addition is variable, averaging 12,000 cells/ day. These new cells account for about 20% of the total increase in retinal area; the remaining 80% is due to hypertrophy, or expansin, of the retina. In contrast to all of the other retinal cells, the rods do not appear to participate in the retinal expansion. This hypothesized immobility of the rods would create a shearing strain between the retinal layers resulting in a shift in their position relative to the other cells. Were they to maintain synaptic contacts with the same horizontal and bipolar cells, the rod axons would have to be elongated peripherally or the post-synaptic cell dendrites displaced centrally. Since neurons with this morphology have not been found in the goldfish retina, these observations suggest that the rods must be changing their synaptic connections as the retina grows.en_US
dc.format.extent1296020 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWiley Subscription Services, Inc., A Wiley Companyen_US
dc.subject.otherLife and Medical Sciencesen_US
dc.subject.otherNeuroscience, Neurology and Psychiatryen_US
dc.titleGrowth of the adult goldfish eye. III. Source of the new retinal cellsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumUniversity of Michigan, Division of Biological Science, Ann Arbo, Michigan 48109en_US
dc.identifier.pmid915042en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/50002/1/901760304_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/cne.901760304en_US
dc.identifier.sourceThe Journal of Comparative Neurologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Show simple item record