Development of synaptic arrays in the inner plexiform layer of neonatal mouse retina
dc.contributor.author | Fisher, Leslie J. | en_US |
dc.date.accessioned | 2007-04-06T18:17:25Z | |
dc.date.available | 2007-04-06T18:17:25Z | |
dc.date.issued | 1979-09-15 | en_US |
dc.identifier.citation | Fisher, Leslie J. (1979)."Development of synaptic arrays in the inner plexiform layer of neonatal mouse retina." The Journal of Comparative Neurology 187(2): 359-372. <http://hdl.handle.net/2027.42/50007> | en_US |
dc.identifier.issn | 0021-9967 | en_US |
dc.identifier.issn | 1096-9861 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/50007 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=489784&dopt=citation | en_US |
dc.description.abstract | Retinas from mice of the C57BL/6 strain were sampled at frequent intervals from birth to postnatal day 33 to determine the numerical density of conventional and ribbon synapses within the inner plexiform layer (IPL) as a function of time. Synaptic arrays of the IPL were formed in three phases. During Phase I, from day 3 to day 10, conventional synapses were produced at a mean rate of 0.44 synapses/1,000 Μm 3 /hour, but no ribbons were seen. During Phase II, from day 11 to day 15, ribbons formed at a rate of 0.38 ribbons/1,000 Μm 3 /hour and conventional synapses were produced at a rate of 1.15 synapses/1,000 Μm 3 /hour. Phase III began at day 15, the approximate time of eye opening in these animals, and was characterized by a sharp reduction in the rate of production of both ribbons and conventional synapses. During this phase ribbons achieved a final mean density of 113 ribbons/1,000 Μm 3 and conventionals achieved a final mean density of 250 synapses/1,000 Μm 3 . Serial synapses appeared in Phase II but remained at low densities. | en_US |
dc.format.extent | 889530 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | The Wistar Institute of Anatomy and Biology | en_US |
dc.publisher | Wiley Periodiocals, Inc. | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Neuroscience, Neurology and Psychiatry | en_US |
dc.title | Development of synaptic arrays in the inner plexiform layer of neonatal mouse retina | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | The University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.identifier.pmid | 489784 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/50007/1/901870207_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/cne.901870207 | en_US |
dc.identifier.source | The Journal of Comparative Neurology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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