Connections of the corticomedial amygdala in the golden hamster. II. Efferents of the “olfactory amygdala”

Abstract

The anterior cortical (C1) and posterolateral cortical (C2) nuclei of the amygdala are designated the “olfactory amygdala” because they each receive direct projections from the main olfactory bulb. The efferents of these nuclei were traced after sterotaxic placement of 1—5 ΜCi tritiated proline in the corticomedial amygdala of male golden hamsters. Following survival times of 12, 24, or 48 hours, 20 Μm frozen sections of the brains were processed for light microscopic autoradiography. Efferents from C2 terminate in layers II and III of the olfactory tubercle and in layer lb of pars ventralis and pars medialis of the anterior olfactory nucleus. Fibers from this nucleus also project to layers I and II of the infralimbic cortex and to the molecular layer of the agranular insular cortex. More posteriorly, fibers from C2 teminate in layer I of the dorsolateral entorhinal cortex, and in the endopiriform nucleus. From C1, efferent fibers travel in the stria terminalis and terminate in the precommissural bed nucleus of the stria terminalis and in the mediobasal hypothalamus. Efferents from C1 also innervate the molecular layer of C2, the amygdalo-hippocampal area, and the adjacent piriform cortex. Neurons in both C1 and C2 project to the molecular layer of the medial amygdaloid nucleus and the posteromedial cortical nucleus of the amygdala, the plexiform layer of the ventral subiculum, and the molecular layer of the lateral entorhinal cortex.