Show simple item record

Neurons of origin and fiber trajectory of amygdalofugal projections to the medial preoptic area in syrian hamsters

dc.contributor.authorMaragos, William F.en_US
dc.contributor.authorNewman, Sarah Winansen_US
dc.contributor.authorLehman, Michael N.en_US
dc.contributor.authorPowers, J. Bradleyen_US
dc.date.accessioned2007-04-06T18:21:19Z
dc.date.available2007-04-06T18:21:19Z
dc.date.issued1989-02-01en_US
dc.identifier.citationMaragos, William F.; Newman, Sarah Winans; Lehman, Michael N.; Powers, J. Bradley (1989)."Neurons of origin and fiber trajectory of amygdalofugal projections to the medial preoptic area in syrian hamsters." The Journal of Comparative Neurology 280(1): 59-71. <http://hdl.handle.net/2027.42/50043>en_US
dc.identifier.issn0021-9967en_US
dc.identifier.issn1096-9861en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/50043
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2918096&dopt=citationen_US
dc.description.abstractThe amygdaloid neurons of origin and the trajectory of amygdaloid fibers to the medial preoptic area of the adult male Syrian hamster were identified by using horseradish peroxidase (HRP) histochemistry. After iontophoresis of HRP into the medial preoptic area, retrogradely labeled amygdaloid neurons were located in the dorsal and caudal parts of the medial amygdaloid nucleus and throughout the amygdalohippocampal area. No amygdaloid neurons were labeled after HRP applications confined to the most rostral portion of the medial preoptic area (anterior to the body of the anterior commissure). Following more caudal medial preoptic area injections (body of the anterior commissure to the suprachiasmatic nucleus) the distribution of retrogradely labeled cells in the medial amygdaloid nucleus and the amygdalohippocampal area revealed no topographic organization of the amygdalopreoptic connections. When amygdaloid neurons were labeled, the amygdalohippocampal area contained two to five times as many HRP-filled cells as the medial amygdaloid nucleus. Retrogradely transported HRP could be followed from the medial preoptic area to the amygdala through fibers in the dorsomedial quadrant of the stria terminalis. In addition, electrolytic lesions of the stria terminalis prior to iontophoresis of HRP into the medial preoptic area prevented retrograde transport to neurons in both the dorsocaudal medial amygdaloid nucleus and the amygdalohippocampal area. These results confirm earlier observations describing the location of autoradiographically labeled efferents from the medial amygdaloid nucleus to the medial preoptic area and provide new information about the restricted region within the medial amygdaloid nucleus from which these projections arise. They also suggest that, unlike the projections from the medial amygdaloid nucleus to the bed nucleus of the stria terminalis, the efferents to the medial preoptic area travel entirely in the stria terminalis.en_US
dc.format.extent3844172 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherAlan R. Liss, Inc.en_US
dc.publisherWiley Periodiocals, Inc.en_US
dc.subject.otherLife and Medical Sciencesen_US
dc.subject.otherNeuroscience, Neurology and Psychiatryen_US
dc.titleNeurons of origin and fiber trajectory of amygdalofugal projections to the medial preoptic area in syrian hamstersen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Anatomy and Cell Biology, Medical Science II, University of Michigan Medical School, Ann Arbor, Michigan 48109–0616en_US
dc.contributor.affiliationumDepartment of Anatomy and Cell Biology, Medical Science II, University of Michigan Medical School, Ann Arbor, Michigan 48109–0616en_US
dc.contributor.affiliationumDepartment of Anatomy and Cell Biology, Medical Science II, University of Michigan Medical School, Ann Arbor, Michigan 48109–0616en_US
dc.contributor.affiliationumDepartment of Anatomy and Cell Biology, Medical Science II, University of Michigan Medical School, Ann Arbor, Michigan 48109–0616en_US
dc.identifier.pmid2918096en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/50043/1/902800106_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/cne.902800106en_US
dc.identifier.sourceThe Journal of Comparative Neurologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Show simple item record