Show simple item record

Distribution and projection pattern of motoneurons that innervate hindlimb muscles in the quail

dc.contributor.authorTyrrell, Sophiaen_US
dc.contributor.authorSchroeter, Sallyen_US
dc.contributor.authorCoulter, Lynnen_US
dc.contributor.authorTosney, Kathryn W.en_US
dc.date.accessioned2007-04-06T18:21:45Z
dc.date.available2007-04-06T18:21:45Z
dc.date.issued1990-08-15en_US
dc.identifier.citationTyrrell, Sophia; Schroeter, Sally; Coulter, Lynn; Tosney, Kathryn W. (1990)."Distribution and projection pattern of motoneurons that innervate hindlimb muscles in the quail." The Journal of Comparative Neurology 298(4): 413-430. <http://hdl.handle.net/2027.42/50047>en_US
dc.identifier.issn0021-9967en_US
dc.identifier.issn1096-9861en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/50047
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2229473&dopt=citationen_US
dc.description.abstractWe characterized the motoneuron pool positions and projection patterns in the embryonic quail hindlimb and compared them to those in the chick to determine the degree of similarity and to form a baseline for future chimeric experiments. We find that the most similar parameters of pool position correlate with the major axonal pathway choices. First, the medial-lateral pool position, which is highly conserved among birds and mammals, is identical in the quail and chick and correlates with the dorsal-ventral pathway choice, the first and least plastic of the choices within the limb. Second, although quail pools were known to be compressed into seven rather than eight segments, we show that the map of pools is compressed about a central point (segment three) that preserves the spatial relationships between anterior pools and the crural plexus, and between posterior pools and the sciatic plexus. Access to guidance cues that are restricted to each plexus region is thus maintained between species. Third, pool position along the anterior-posterior axis is the least similar parameter between species. In fact, the entire lumbosacral motor complex may shift by ± half a segment in individual quail. Despite the consequent differences in segmental projections, the specific projection pattern within each quail hindlimb is identical to that in the chick. There is no need to preserve the exact segmental pattern either phylogenetically or during development, because motoneurons accommodate to modest variations in their position along the anterior-posterior axis by sorting out at the limb base. The contrast between variable segmental and constant limb projections also demonstrates that neither the specification nor the precise projection of motoneurons is dependent upon the specification or development of somites.en_US
dc.format.extent2248319 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWiley Subscription Services, Inc., A Wiley Companyen_US
dc.subject.otherLife and Medical Sciencesen_US
dc.subject.otherNeuroscience, Neurology and Psychiatryen_US
dc.titleDistribution and projection pattern of motoneurons that innervate hindlimb muscles in the quailen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Biology, The University of Michigan, Ann Arbor, Michigan 48109en_US
dc.contributor.affiliationumDepartment of Biology, The University of Michigan, Ann Arbor, Michigan 48109en_US
dc.contributor.affiliationumDepartment of Biology, The University of Michigan, Ann Arbor, Michigan 48109en_US
dc.contributor.affiliationumDepartment of Biology, The University of Michigan, Ann Arbor, Michigan 48109 ; Natural Science Building, University of Michigan, Ann Arbor, MI 48109en_US
dc.identifier.pmid2229473en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/50047/1/902980404_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/cne.902980404en_US
dc.identifier.sourceThe Journal of Comparative Neurologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Show simple item record