Transport of proteins and sulfated mucopolysaccharides in the goldfish visual system This paper was presented at a symposium on axoplasmic flow at the second meeting of the American Society for Neurochemistry, Hershey, Pennsylvania, March 15, 1971 This work was supported by grant MH 12506 of the National Institute of Mental Health and GB-5125X of the National Science Foundation.

Abstract

3 H-Proline, 3 H-asparagine and Na 2 35 SO 4 have been found to be highly specific markers for axonal transport in the goldfish visual system. The amino acids label both rapidly and slowly transported proteins while the 35 S is recovered mainly with the rapidly transported materials, including protein-bound mucopolysaccharides. These precursors have been used to study the rate of transport, the subcellular distribution and the rate of turnover of transported proteins in the nerve terminals.