Renal transport of glucose by the aglomerular fish Lophius americanus This investigation was supported by U. S. Public Health Grant A-3885 and by Nonr-1224(26).

Abstract

The renal excretion of glucose by the aglomerular fish Lophius americanus was studied. It was found that glucose is a normal constituent of Lophius urine . U/P ratios were approximately 0.02. However, after elevation of plasma glucose level or injection of phlorizin the U/P ratio for glucose was increased as much as ten fold. This increase in U/P ratio was observed even if urine was collected directly from the ureter rather than from the bladder. These results are consistent with the hypothesis that glucose is able to diffuse across the renal tubular epithelium, which also has the ability to reabsorb glucose which diffuses into the urine.