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Plasma exchange in chronic inflammatory demyelinating polyradiculoneuropathy

dc.contributor.authorDonofrio, Peter D.en_US
dc.contributor.authorTandan, Rupen_US
dc.contributor.authorAlbers, James W.en_US
dc.date.accessioned2007-04-06T18:30:49Z
dc.date.available2007-04-06T18:30:49Z
dc.date.issued1985-05en_US
dc.identifier.citationDonofrio, Peter D.; Tandan, Rup; Albers, James W. (1985)."Plasma exchange in chronic inflammatory demyelinating polyradiculoneuropathy." Muscle & Nerve 8(4): 321-327. <http://hdl.handle.net/2027.42/50135>en_US
dc.identifier.issn0148-639Xen_US
dc.identifier.issn1097-4598en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/50135
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=16758599&dopt=citationen_US
dc.description.abstractEleven consecutive patients with progressive chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) underwent plasma exchange. Eight patients were previously unresponsive to prednisone, two were started on prednisone with plasma exchange, and one did not receive corticosteroids. Electrodiagnostic studies revealed evidence of an acquired demyelinating polyradiculoneuropathy with varying degrees of axonal degeneration. Neurologic impairment was monitored using conventional functional status index. Five patients demonstrated substantial clinical improvement, beginning 2 days to 3 weeks after initiating plasma exchange. Two additional patients improved following a second course of plasma exchange, and four patients demonstrated minimal or no change. Comparison of responding and onresponding patients showed no differences related to the presence or absence of antecedent illness, duration of disease, duration of maximum weakness, or severity of impairment prior to plasma exchange. Responders had significantly prolonged F-response and motor distal latencies compared to nonresponders. Results in this unselected, consecutive patient trial suggest a temporal relationship between plasma exchange and clinical improvement in some patients with progressive CIDP.en_US
dc.format.extent597215 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWiley Subscription Services, Inc., A Wiley Companyen_US
dc.subject.otherLife and Medical Sciencesen_US
dc.subject.otherNeuroscience, Neurology and Psychiatryen_US
dc.titlePlasma exchange in chronic inflammatory demyelinating polyradiculoneuropathyen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Neurology, University of Michigan, Ann Arbor, MI ; Department of Neurology, University of Michigan Medical Center, B4954 CFOB, Box M056, Ann Arbor, MI 48109–0010en_US
dc.contributor.affiliationumDepartment of Neurology, University of Michigan, Ann Arbor, MIen_US
dc.contributor.affiliationumDepartment of Neurology, University of Michigan, Ann Arbor, MIen_US
dc.identifier.pmid16758599en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/50135/1/880080409_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/mus.880080409en_US
dc.identifier.sourceMuscle & Nerveen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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