Contractile properties of standard and nerve-intact muscle grafts in the rat
Faulkner, John A.; Carlson, Bruce M.
1985-06
Citation
Faulkner, John A.; Carlson, Bruce M. (1985)."Contractile properties of standard and nerve-intact muscle grafts in the rat." Muscle & Nerve 8(5): 413-418. <http://hdl.handle.net/2027.42/50136>
Abstract
The contractile properties of standard and nerve-intact grafts of extensor digitorum longus muscles of rats were compared in vitro. Fourteen days after grafting, the time to peak tension and the half-relaxation times of nerve-intact grafts were shorter than those of standard grafts, but both were longer than control values. By 60 days, these variables attained normal values. At every sample period, the tetanic tensions of nerve-intact grafts were higher than those of standard grafts. Even at the early sampling periods, the twitch-tetanic tension ratios of nerve-intact grafts were close to normal values, whereas those of standard grafts were higher than normal. Stabilized nerve-intact grafts had a larger mass and greater maximum tetanic tension development than standard grafts, but were more fatigable. Compared with control EDL muscles, stable nerve-intact grafts show no differences except for lessened fatigability, whereas standard grafts demonstrate significant functional deficits.Publisher
Wiley Subscription Services, Inc., A Wiley Company
ISSN
0148-639X 1097-4598
Other DOIs
PMID
16758588
Types
Article
URI
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=16758588&dopt=citationMetadata
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