Cells and cell-interactions that guide motor axons in the developing chick embryo

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dc.contributor.author Tonsey, Karthryn W. en_US
dc.date.accessioned 2007-04-06T18:37:00Z
dc.date.available 2007-04-06T18:37:00Z
dc.date.issued 1991-01 en_US
dc.identifier.citation Tonsey, Karthryn W. (1991)."Cells and cell-interactions that guide motor axons in the developing chick embryo." BioEssays 13(1): 17-23. <http://hdl.handle.net/2027.42/50192> en_US
dc.identifier.issn 0265-9247 en_US
dc.identifier.issn 1521-1878 en_US
dc.identifier.uri http://hdl.handle.net/2027.42/50192
dc.description.abstract A considerable challenge confronts, any developing neuron. Before it can establish a functional and specific connection, it must extend an axon over tens and sometimes hundreds of microns through a complex and mutable environment to reach one out of many possible destinations. The field of axonal guidance concerns the control of this navigation process. To satisfactorily identify the cell interactions and molecular mechanisms that mediate axonal guidance, it is essential to first identify the pertinent cell populations. Embryonic surgeries have provided solid information on which tissues are critical and which are irrelevant to the navigation of motor axons within the chick embryo. The gross anatomical nerve pattern is established as axons respond to both positive (path) and negative (barrier) tissue environments. Analysis of the interactions of motoneurons with these tissues reveals that several cellular interactions – chemotaxis, substratum preference, and perhaps contact paralysis – are important to the common patterns of motor axon advance. Axons simultaneously interact with population-specific cues that have begun to be identified on the tissue level. en_US
dc.format.extent 962121 bytes
dc.format.extent 3118 bytes
dc.format.mimetype application/pdf
dc.format.mimetype text/plain
dc.publisher Wiley Subscription Services, Inc., A Wiley Company en_US
dc.subject.other Life and Medical Sciences en_US
dc.subject.other Cell & Developmental Biology en_US
dc.title Cells and cell-interactions that guide motor axons in the developing chick embryo en_US
dc.type Article en_US
dc.rights.robots IndexNoFollow en_US
dc.subject.hlbsecondlevel Ecology and Evolutionary Biology en_US
dc.subject.hlbsecondlevel Molecular, Cellular and Developmental Biology en_US
dc.subject.hlbsecondlevel Natural Resources and Environment en_US
dc.subject.hlbtoplevel Science en_US
dc.subject.hlbtoplevel Health Sciences en_US
dc.description.peerreviewed Peer Reviewed en_US
dc.contributor.affiliationum Biology Department, The University of Michigan, Ann Arbor, MI 48109, USA en_US
dc.description.bitstreamurl http://deepblue.lib.umich.edu/bitstream/2027.42/50192/1/950130104_ftp.pdf en_US
dc.identifier.doi http://dx.doi.org/10.1002/bies.950130104 en_US
dc.identifier.source BioEssays en_US
dc.owningcollname Interdisciplinary and Peer-Reviewed
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