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Specifying the target identity of motoneurons

dc.contributor.authorTosney, Kathryn W.en_US
dc.contributor.authorHotary, Kevin B.en_US
dc.contributor.authorLance-Jones, Cynthiaen_US
dc.date.accessioned2007-04-06T18:37:19Z
dc.date.available2007-04-06T18:37:19Z
dc.date.issued1995-05en_US
dc.identifier.citationTosney, Kathryn W.; Hotary, Kevin B.; Lance-Jones, Cynthia (1995)."Specifying the target identity of motoneurons." BioEssays 17(5): 379-382. <http://hdl.handle.net/2027.42/50194>en_US
dc.identifier.issn0265-9247en_US
dc.identifier.issn1521-1878en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/50194
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7786283&dopt=citationen_US
dc.description.abstractIn the vertebrate spinal cord, motoneurons are clustered into longitudinal columns in agreement with the targets they innervate. Motoneurons within each column acquire properties early in development that ensure their axons navigate to appropriate targets, but how this target identity is specified is unknown. Recently, Tsuchida et al. (1) described the expression of putative regulatory genes within motor columns in the chicken spinal cord. Combinations of LIM-family homeobox genes differentially mark columns that project to distinct target groups. Expression precedes column formation and axon outgrowth, making these genes candidates for specifying the target identity of motoneuron groups.en_US
dc.format.extent479376 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWiley Subscription Services, Inc., A Wiley Companyen_US
dc.subject.otherLife and Medical Sciencesen_US
dc.subject.otherCell & Developmental Biologyen_US
dc.titleSpecifying the target identity of motoneuronsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumBiology Department, The University of Michigan, Ann Arbor, Ml 48109-1048, USAen_US
dc.contributor.affiliationumBiology Department, The University of Michigan, Ann Arbor, Ml 48109-1048, USAen_US
dc.contributor.affiliationotherDepartment of Neurobiology, The University of Pittsburgh, School of Medicine, Pittsburgh, PA 15261, USAen_US
dc.identifier.pmid7786283en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/50194/1/950170503_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/bies.950170503en_US
dc.identifier.sourceBioEssaysen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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