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Transmission of mitochondrial DNA - playing favorites?

dc.contributor.authorBoore, Jeffrey L.en_US
dc.date.accessioned2007-04-06T18:37:38Z
dc.date.available2007-04-06T18:37:38Z
dc.date.issued1997-09en_US
dc.identifier.citationBoore, Jeffrey L. (1997)."Transmission of mitochondrial DNA - playing favorites?." BioEssays 19(9): 751-753. <http://hdl.handle.net/2027.42/50197>en_US
dc.identifier.issn0265-9247en_US
dc.identifier.issn1521-1878en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/50197
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=9297965&dopt=citationen_US
dc.description.abstractMitochondria are essential subcellular organelles containing an extranuclear genome (mtDNA). Mutations in mtDNA have recently been identified as causing a variety of human hereditary diseases. In most of these cases, the tissues of the affected individual contain a mixture of mutant and normal mtDNA, with this ratio determining the severity of symptoms. Stochastic factors alone have generally been believed to determine this ratio. Jenuth et al. (1) , however, examining mice that contain a mixture of mtDNA types, show evidence of strong selective forces at work in favoring one mtDNA variant over another in some tissues.en_US
dc.format.extent503395 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWiley Subscription Services, Inc., A Wiley Companyen_US
dc.subject.otherLife and Medical Sciencesen_US
dc.subject.otherCell & Developmental Biologyen_US
dc.titleTransmission of mitochondrial DNA - playing favorites?en_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Biology, University of Michigan, 830 N. University Ave., Ann Arbor, MI 48109, USAen_US
dc.identifier.pmid9297965en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/50197/1/950190904_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/bies.950190904en_US
dc.identifier.sourceBioEssaysen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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