Transmission of mitochondrial DNA - playing favorites?
dc.contributor.author | Boore, Jeffrey L. | en_US |
dc.date.accessioned | 2007-04-06T18:37:38Z | |
dc.date.available | 2007-04-06T18:37:38Z | |
dc.date.issued | 1997-09 | en_US |
dc.identifier.citation | Boore, Jeffrey L. (1997)."Transmission of mitochondrial DNA - playing favorites?." BioEssays 19(9): 751-753. <http://hdl.handle.net/2027.42/50197> | en_US |
dc.identifier.issn | 0265-9247 | en_US |
dc.identifier.issn | 1521-1878 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/50197 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=9297965&dopt=citation | en_US |
dc.description.abstract | Mitochondria are essential subcellular organelles containing an extranuclear genome (mtDNA). Mutations in mtDNA have recently been identified as causing a variety of human hereditary diseases. In most of these cases, the tissues of the affected individual contain a mixture of mutant and normal mtDNA, with this ratio determining the severity of symptoms. Stochastic factors alone have generally been believed to determine this ratio. Jenuth et al. (1) , however, examining mice that contain a mixture of mtDNA types, show evidence of strong selective forces at work in favoring one mtDNA variant over another in some tissues. | en_US |
dc.format.extent | 503395 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Cell & Developmental Biology | en_US |
dc.title | Transmission of mitochondrial DNA - playing favorites? | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Biology, University of Michigan, 830 N. University Ave., Ann Arbor, MI 48109, USA | en_US |
dc.identifier.pmid | 9297965 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/50197/1/950190904_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/bies.950190904 | en_US |
dc.identifier.source | BioEssays | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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