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A scanning electron microscopic and quantitative histologic description of lens regeneration in the newt, Notophthalmus viridescens

dc.contributor.authorConnelly, Thomas G.en_US
dc.date.accessioned2007-04-06T18:46:02Z
dc.date.available2007-04-06T18:46:02Z
dc.date.issued1978-10en_US
dc.identifier.citationConnelly, Thomas G. (1978)."A scanning electron microscopic and quantitative histologic description of lens regeneration in the newt, Notophthalmus viridescens ." Journal of Morphology 158(1): 31-40. <http://hdl.handle.net/2027.42/50271>en_US
dc.identifier.issn0362-2525en_US
dc.identifier.issn1097-4687en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/50271
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=722789&dopt=citationen_US
dc.description.abstractAdult newts ( Notophthalmus viridescens ) were lentectomized and at intervals from 4 to 21 days after lentectomy iridocorneal complexes from these animals were examined by scanning electron microscopy to allow a full appreciation for the shape of the regenerating lens. Until around day 12 after lentectomy the posterior surface of the iris is covered by a dense mat of fibrous material which cannot be removed without damage to the iris and which obscures the events of cytoplasmic shedding. The regenerate becomes visible first around stage IV (day 12). A small but clear groove demarcates the regenerate from the rest of the iris. As regeneration progresses there is a marked reduction in debris on the iris surface and the regenerate appears as a U-shaped thickening occupying about one-third of the dorsal half of the iris. During later stages (VI–X) the regenerate protrudes into the pupil inferiorly and posteriorly towards the retina, but does not encroach laterally on the remaining pigmented iris tissue. Prior to secretion of the lens capsule the outline of individual cells is visible on the surface of the regenerate and some regenerates exhibit a prominent dimple on their posterior aspects. Following secretion of the capsule the surface of the regenerate becomes smooth. Quantitative studies show that volume and maximum section area of the regenerate are both more strongly correlated with developmental stage of regeneration than with time after lentectomy.en_US
dc.format.extent854294 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWiley Subscription Services, Inc., A Wiley Companyen_US
dc.subject.otherLife and Medical Sciencesen_US
dc.subject.otherCell & Developmental Biologyen_US
dc.titleA scanning electron microscopic and quantitative histologic description of lens regeneration in the newt, Notophthalmus viridescensen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Anatomy, and Center for Human Growth and Development, The University of Michigan, Ann Arbor, Michigan 48109en_US
dc.identifier.pmid722789en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/50271/1/1051580104_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/jmor.1051580104en_US
dc.identifier.sourceJournal of Morphologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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