Lidase treatment of spinal cord transected rats
dc.contributor.author | Kowalski, Timothy F. | en_US |
dc.contributor.author | Lee Vahlsing, H. | en_US |
dc.contributor.author | Feringa, Earl R. | en_US |
dc.date.accessioned | 2007-04-06T18:48:48Z | |
dc.date.available | 2007-04-06T18:48:48Z | |
dc.date.issued | 1979-07 | en_US |
dc.identifier.citation | Kowalski, Timothy F.; Lee Vahlsing, H.; Feringa, Earl R. (1979)."Lidase treatment of spinal cord transected rats." Annals of Neurology 6(1): 78-79. <http://hdl.handle.net/2027.42/50295> | en_US |
dc.identifier.issn | 0364-5134 | en_US |
dc.identifier.issn | 1531-8249 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/50295 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=507763&dopt=citation | en_US |
dc.description.abstract | Russian investigators have recently reported clinical recovery of enzyme treated, spinal cord transected rats. Using the exact protocols outlined by Matinian and Andreasian, we repeated a portion of their experiment using a Lidase preparation manufactured in the USSR. Animals were evaluated for return of bladder function, clinical evidence of hind limb motor function, cortical evoked response after sciatic nerve stimulation, and axonal transport of cortically injected tritiated proline by regenerated corticospinal axons. The only difference between treated and control animals was that the mean total body weight of the treated animals increased more than that of controls ( p < 0.05). No animal walked, had return of voluntary motor activity, showed cortical evoked response, or had evidence for transport of tritiated proline over regenerated corticospinal axons. | en_US |
dc.format.extent | 233092 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Neuroscience, Neurology, and Psychiatry | en_US |
dc.title | Lidase treatment of spinal cord transected rats | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Psychiatry | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Departments of Neurology and Pathology, Ann Arbor Veterans Administration and University of Michigan Medical Centers, Ann Arbor, MI | en_US |
dc.contributor.affiliationum | Departments of Neurology and Pathology, Ann Arbor Veterans Administration and University of Michigan Medical Centers, Ann Arbor, MI | en_US |
dc.contributor.affiliationum | Departments of Neurology and Pathology, Ann Arbor Veterans Administration and University of Michigan Medical Centers, Ann Arbor, MI ; Chief, Neurology Service (127), Veterans Administration Medical Center, 2215 Fuller Rd, Ann Arbor, MI 48105 | en_US |
dc.identifier.pmid | 507763 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/50295/1/410060121_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/ana.410060121 | en_US |
dc.identifier.source | Annals of Neurology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.