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A regional metabolic contrast method for the study of brain pathology

dc.contributor.authorAgranoff, Bernard W.en_US
dc.contributor.authorFrey, Kirk A.en_US
dc.date.accessioned2007-04-06T18:50:02Z
dc.date.available2007-04-06T18:50:02Z
dc.date.issued1984en_US
dc.identifier.citationAgranoff, Bernard W.; Frey, Kirk A. (1984)."A regional metabolic contrast method for the study of brain pathology." Annals of Neurology 15(S1): 93-97. <http://hdl.handle.net/2027.42/50307>en_US
dc.identifier.issn0364-5134en_US
dc.identifier.issn1531-8249en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/50307
dc.description.abstractThe use of 2-deoxyglucose for the measurement of regional cerebral glucose utilization in both animals and humans has gained widespread application. An attractive aspect of regional brain glucose metabolism is its apparent correlation with functional activity in neurons. Animal experiments suggest that this relationship is altered in brain lesions and that barbiturate anesthesia may be employed in the detection of brain regions where uncoupling of metabolism and neuronal function has occurred. A functional metabolic contrast technique is described that will permit determination of regional metabolism that is specifically attributable to neuronal activity. Areas of potential clinical application are discussed.en_US
dc.format.extent2119658 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWiley Subscription Services, Inc., A Wiley Companyen_US
dc.subject.otherLife and Medical Sciencesen_US
dc.subject.otherNeuroscience, Neurology, and Psychiatryen_US
dc.titleA regional metabolic contrast method for the study of brain pathologyen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPsychiatryen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumNeuroscience Laboratory, Mental Health Research Institute, University of Michigan, Ann Arbor, MI 48109 ; Neuroscience Laboratory Building, University of Michigan, 1103 East Huron Ave, Ann Arbor, MI 48109en_US
dc.contributor.affiliationumNeuroscience Laboratory, Mental Health Research Institute, University of Michigan, Ann Arbor, MI 48109en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/50307/1/410150717_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/ana.410150717en_US
dc.identifier.sourceAnnals of Neurologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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