Immunosuppressive treatment in multifocal motor neuropathy
Feldman, Eva L.; Bromberg, Mark B.; Albers, James W.; Pestronk, Alan
1991-09
Citation
Feldman, Eva L.; Bromberg, Mark B.; Albers, James W.; Pestronk, Alan (1991)."Immunosuppressive treatment in multifocal motor neuropathy." Annals of Neurology 30(3): 397-401. <http://hdl.handle.net/2027.42/50344>
Abstract
We report the results of immunosuppressive treatments of 13 patients with multifocal motor neuropathy and elevated titers of serum antibodies to the GM1 ganglioside. All patients failed to respond to oral prednisone. There was no clinical response in 4 patients treated with plasma exchange. Nine patients received cyclophosphamide, with clinical improvement and fall in antibody titers in 8. In 3 patients, cyclophosphamide was discontinued with ensuing clinical relapse and rise in the titers of serum anti-GM1 antibodies. These patients provide further evidence for the efficacy of cyclophosphamide therapy in patients with multifocal motor neuropathy.Publisher
Wiley Subscription Services, Inc., A Wiley Company
ISSN
0364-5134 1531-8249
Other DOIs
PMID
1952828
Types
Article
Metadata
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