Now showing items 1-10 of 12
Prevalence of radiologically defined osteoarthritis in the finger and wrist joints of adult residents of Tecumseh, Michigan, 1962-65
(Elsevier, 1988)
Radiographs of the fingers and wrists of adult participants in the Tecumseh Community Health Study in 1962-1965 were examined for signs of osteoarthritis (OA). The severity of OA for each of 32 joints of the fingers and ...
Randomization in clinical trials: Conclusions and recommendations
(Elsevier, 1988-12)
The statistical properties of simple (complete) randomization, permuted-block (or simply blocked) randomization, and the urn adaptive biased-coin randomization are summarized. These procedures are contrasted to covariate ...
Modeling and analyzing HIV transmission: the effect of contact patterns
(Elsevier, 1988-12)
A compartmental model is presented for the spread of HIV in a homosexual population divided into subgroups by degree of sexual activity. The model includes constant recruitment rates for the susceptibles in the subgroups. ...
Properties of the urn randomization in clinical trials
(Elsevier, 1988-12)
In this article we review the important statistical properties of the urn randomization (design) for assigning patients to treatment groups in a clinical trial. The urn design is the most widely studied member of the family ...
Neurological abnormalities associated with remote occupational elemental mercury exposure
(Wiley Subscription Services, Inc., A Wiley Company, 1988-11)
We examined 502 subjects, 247 of whom had occupational elemental mercury exposures 20 to 35 years previously, to identify potential exposure-related neurological abnormalities. Few significant ( p < 0.05) differences ...
Effect of ambient humidity on dichotomous sampler coarse/fine ratios
(Elsevier, 1988)
Atmospheric aerosols were measured in August 1983 on Allegheny Mountain and Laurel Hill in southwestern Pennsylvania. Ambient humidity was observed to influence the coarse to fine particle ratios as determined by dichotomous ...
Cerebral hypometabolism in progressive supranuclear palsy studied with positron emission tomography
(Wiley Subscription Services, Inc., A Wiley Company, 1988-09)
Progressive supranuclear palsy (PSP) is characterized by supranuclear palsy of gaze, axial dystonia, bradykinesia, rigidity, and a progressive dementia. Pathological changes in this disorder are generally restricted to ...
Synergism of mutant frequencies in the mouse lymphoma cell mutagenicity assay by binary mixtures of methyl methanesulfonate and ethyl methanesulfonate
(Elsevier, 1988-10)
The effect of mixed mutagen exposures on the rate and type of induced mutants was studied in the L5178Y/TK+/- --> TK-/- mouse lymphoma cell mutagenicity assay. In this assay, exposure to ethyl methanesulfonate (EMS) ...
Benefits and risks of menopausal estrogen and/or progestin hormone use,
(Elsevier, 1988-03)
Current evidence is reviewed here on risks and benefits of estrogen and progestin use by peri- and postmenopausal women in relation to the following conditions: endometrial cancer, breast cancer, osteoporosis, and coronary ...
Retrospective studies in scleroderma: Effect of potassium para-aminobenzoate on survival
(Elsevier, 1988)
Demographic and survival data are presented for 390 patients with scleroderma. For the entire group An estimated, 81.4% survived 5 years from diagnosis and 69.4% survived 10 years. Life-table analyses revealed that adequate ...