Now showing items 31-33 of 33
Integrated Mapping Analysis of the Werner Syndrome Region of Chromosome 8
(Elsevier, 1994-09-01)
The Werner syndrome locus (WRN) is located at 8p11-p12. To facilitate eventual cloning of the WRN gene, a 10,000-rad radiation-reduced hybrid (RH) cell panel was generated to map genetic markers, sequence-tagged sites ...
Affected-sib-pair interval mapping and exclusion for complex genetic traits: Sampling considerations
(Wiley Subscription Services, Inc., A Wiley Company, 1996)
We describe an extension of Risch's [(1990a,b) Am J Hum Genet 46:222–228, 229–241] method of linkage detection and exclusion for complex genetic traits. The method uses interval mapping to infer disease locus identity-by-descent ...
Modest evidence for linkage and possible confirmation of association between NOTCH4 and schizophrenia in a large veterans affairs cooperative study sample
(Wiley Subscription Services, Inc., A Wiley Company, 2003-04-01)
Wei and Hemmings [2000: Nat Genet 25:376–377], using 80 British parent–offspring trios, identified a number of NOTCH4 variants and haplotypes that showed statistically significant evidence of association to schizophrenia. ...