Now showing items 1-10 of 44
A radiation hybrid map of the proximal short arm of the human X chromosome spanning incontinentia pigmenti 1 (IP1) translocation breakpoints
(Elsevier, 1992-11)
Radiation hybrid mapping was used in combination with physical mapping techniques to order and estimate distances between 14 loci in the proximal region of the short arm of the human X chromosome. A panel of radiation ...
Using sex-averaged genetic maps in multipoint linkage analysis when identity-by-descent status is incompletely known
(Wiley Subscription Services, Inc., A Wiley Company, 2006-07)
The ratio of male and female genetic map distances varies dramatically across the human genome. Despite these sex differences in genetic map distances, most multipoint linkage analyses use sex-averaged genetic maps. We ...
Syndrome X: Is it for real?
(Wiley Subscription Services, Inc., A Wiley Company, 1998)
The term syndrome X has been applied to the association of hypertension, non-insulin-dependent diabetes mellitus (NIDDM), android obesity, insulin resistance, and dyslipidemia. In this paper, based on population samples ...
Localization of the Gene for ATP Citrate Lyase (ACLY) Distal to Gastrin (GAS) and Proximal to D17S856 on Chromosome 17q12-q21
(Elsevier, 1994-05-15)
The gene encoding ATP-citrate lyase, designated ACLY, was mapped to human chromosome 17q12-q21 by PCR on a panel of human/rodent somatic cell hybrids and localized to 17q21.1 by PCH on a panel of radiation hybrids. The ...
Tonofilament protein, a keratin from rat epidermis
(Elsevier, 1981-11-16)
Tonofilament protein from newborn rat epidermis was found to be antigenically related to mouse keratins. Tonofilament protein, like keratins, could be extracted with 8 M urea in Tris buffer. The yield was enhanced by the ...
A rapid screening method for the detection of viable spores in powder using bioluminescence
(John Wiley & Sons, Ltd., 2004-07)
A rapid diagnosis of a biological threat in a powder sample is important for first responders who have to make decisions on-site. The present culture-based method does not provide timely results, which is a critical barrier ...
Heat shock factor 1-deficient mice exhibit decreased recovery of hearing following noise overstimulation
(Wiley Subscription Services, Inc., A Wiley Company, 2005-08-15)
Heat shock proteins (Hsps) can enhance cell survival in response to stress. Heat shock factor 1 (Hsf1) is the major transcription factor that regulates stress-inducible Hsp expression. We previously demonstrated the ...
Inner hair cell responses to the velocity of basilar membrane motion in the guinea pig
(Elsevier, 1981-04-27)
Triangular wave acoustic stimulation at 200 Hz produced the expected square wave cochlear microphonic at the round window membrane and within the scala media. Intracellular recordings from inner hair cells (IHC) of the ...
Detection of E. coli in beach water within 1 hour using immunomagnetic separation and ATP bioluminescence
(John Wiley & Sons, Ltd., 2004-01)
The contamination of beach waters occurs from the discharge of storm water and sanitary sewer overflows containing faecal material. Additional faecal material derives from discharge of animals and waterfowl. In order to ...
Haplotype association analysis for late onset diseases using nuclear family data
(Wiley Subscription Services, Inc., A Wiley Company, 2006-04)
In haplotype-based association studies for late onset diseases, one attractive design is to use available unaffected spouses as controls (Valle et al. [1998] Diab. Care 21:949–958). Given cases and spouses only, the standard ...