Now showing items 41-44 of 44
Integrated Mapping Analysis of the Werner Syndrome Region of Chromosome 8
(Elsevier, 1994-09-01)
The Werner syndrome locus (WRN) is located at 8p11-p12. To facilitate eventual cloning of the WRN gene, a 10,000-rad radiation-reduced hybrid (RH) cell panel was generated to map genetic markers, sequence-tagged sites ...
Coordinate control and variation in X-linked gene expression among female mice
(Springer-Verlag; Springer-Verlag New York Inc., 1997-11)
In normal female mammals, one of the two X Chromosome (Chr) homologs per cell is silenced coordinately during early embryogenesis. The genes located on the inactivated X homolog are predicted to be influenced by the same ...
Affected-sib-pair interval mapping and exclusion for complex genetic traits: Sampling considerations
(Wiley Subscription Services, Inc., A Wiley Company, 1996)
We describe an extension of Risch's [(1990a,b) Am J Hum Genet 46:222–228, 229–241] method of linkage detection and exclusion for complex genetic traits. The method uses interval mapping to infer disease locus identity-by-descent ...
MACF1 gene structure: a hybrid of plectin and dystrophin
(Springer-Verlag; Springer-Verlag New York Inc., 2001-11)
Mammalian MACF1 (Macrophin1; previously named ACF7) is a giant cytoskeletal linker protein with three known isoforms that arise by alternative splicing. We isolated a 19.1-kb cDNA encoding a fourth isoform (MACF1-4) with ...