Now showing items 11-20 of 43
Room-temperature preparation and characterization of poly (ethylene glycol)-coated silica nanoparticles for biomedical applications
(Wiley Subscription Services, Inc., A Wiley Company, 2003-09-15)
Monodisperse, spherical, polyethylene glycol (PEG)–coated silica nanoparticles have been prepared at room temperature and characterized for the purpose of biomedical applications. The particles were synthesized by the ...
Detection of oxidative mutagens in an urban air-particulate extract: a preliminary study
(Elsevier, 1992-12)
The Ames assays strains TA98 and TA100 have been useful in characterizing complex mixtures from organic solvent extracts of particles from diesel-powered vehicles, ambient air, and other sources. In this paper we report ...
Lod scores for gene mapping in the presence of marker map uncertainty
(John Wiley & Sons, Inc., 2001-07)
Multipoint lod scores are typically calculated for a grid of locus positions, moving the putative disease locus across a fixed map of genetic markers. Changing the order of a set of markers and/or the distances between the ...
Kinetics of heat inactivation of phenyl valerate hydrolases from hen and rat brain
(Elsevier, 1987-10-01)
Heat inactivation was studied at 45, 50, 55, and 60[deg] for all of the phenyl valerate hydrolases (PVase), including neurotoxic esterase (NTE) and inhibitor-resistant esterase (IRE), in homogenates of hen or rat brain or ...
Assessment of sex-specific genetic and environmental effects on bone mineral density
(Wiley Subscription Services, Inc., A Wiley Company, 2004-09)
Although it is widely accepted that genes contribute significantly to the variation in bone mineral density (BMD), the nature of the genetic contribution is poorly defined. There are large gender differences in BMD, although ...
An evaluation of the replicate pool method: quick estimation of genome-wide linkage peak p -values
(Wiley Subscription Services, Inc., A Wiley Company, 2006-05)
The calculation of empirical p -values for genome-wide non-parametric linkage tests continues to present significant computational challenges for many complex disease mapping studies. The gold standard approach is to use ...
Synergism of mutant frequencies in the mouse lymphoma cell mutagenicity assay by binary mixtures of methyl methanesulfonate and ethyl methanesulfonate
(Elsevier, 1988-10)
The effect of mixed mutagen exposures on the rate and type of induced mutants was studied in the L5178Y/TK+/- --> TK-/- mouse lymphoma cell mutagenicity assay. In this assay, exposure to ethyl methanesulfonate (EMS) ...
Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in Finns
(Springer-Verlag, 2005-11)
Mitochondria play an integral role in ATP production in cells and are involved in glucose metabolism and insulin secretion, suggesting that variants in the mitochondrial genome may contribute to diabetes susceptibility. ...