Now showing items 31-40 of 43
Radiation hybrid map spanning the huntington disease gene region of chromosome 4Radiation hybrid map spanning the huntington disease gene region of chromosome 4
(Elsevier, 1992-08)
Radiation hybrid (RH) mapping was used to construct a map of 11 markers in the distal 4 Mb of the short arm of chromosome 4, the region containing the Huntington disease gene. Two different methods for deriving the order ...
Cohort follow-up using computer linkage with routinely collected data
(Elsevier, 1981)
The validation of a computerised record linkage system for matching members of a defined cohort with routinely collected national data sources is reported for the first time. The two national sources relate to mortality ...
Circadian fluctuation of plasma epinephrine in supine humans
(Elsevier, 1987)
Previous studies have demonstrated circadian fluctuations of systemic catecholamines in man. However, methodological differences and conflicting results with epinephrine are apparent. In the present study, plasma and urinary ...
Linkage analysis of von Recklinghausen neurofibromatosis to DNA markers on chromosome 17
(Elsevier, 1987-12)
Several recent studies indicate that the von Recklinghausen neurofibromatosis (NF1) gene is located near the centromere of chromosome 17 in some families. However, variable expressivity and a very high mutation rate suggest ...
Commingling and segregation analyses: Comparison of results from a simulation study of a quantitative trait
(Wiley Subscription Services, Inc., A Wiley Company, 1990)
Commingling analysis is commonly used to provide preliminary evidence for a single genetic locus with a major effect on the quantitative trait of interest. In this paper, the effectiveness of commingling analysis as a ...
A radiation hybrid map of the region on human chromosome 22 containing the neurofibromatosis type 2 locus
(Elsevier, 1992-11)
We describe a high-resolution radiation hybrid map of the region on human chromosome 22 containing the neurofibromatosis type 2 (NF2) gene. Eighty-five hamster--human somatic cell hybrids generated by X-irradiation and ...
Physical mapping of the nail patella syndrome interval at 9q34: ordering of STSs and ESTs
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1998-11)
The murine situs inversus viscerum (iv) gene responsible for visceral asymmetry is linked tightly to the Igh-C cluster on chromosome 12
(Elsevier, 1990-07)
The iv gene controls left-right determination during murine organogenesis. To map this gene, we analyzed backcross progeny produced by mating (C57BL/6J x MEV/Ty)F1-iv/+ heterozygotes to C57BL/6J-iv homozygotes. Hybridization ...
Tag SNP selection for Finnish individuals based on the CEPH Utah HapMap database
(Wiley Subscription Services, Inc., A Wiley Company, 2006-02)
The pattern and nature of linkage disequilibrium in the human genome is being studied and catalogued as part of the International HapMap Project [:2003 Nature 426:789–796]. A key goal of the HapMap Project is to enable ...