Now showing items 1-10 of 40
Composition and origin of summertime air pollutants at Deep Creek Lake, Maryland
(Elsevier, 1989)
A 1 month intensive summertime field study conducted in rural western Maryland resulted in a comprehensive set of fine particle, gaseous and meteorological data. Sulfur in the assumed form of ammonium sulfate accounted for ...
Non-parametric estimation of gap time survival functions for ordered multivariate failure time data
(John Wiley & Sons, Ltd., 2004-06-30)
Times between sequentially ordered events (gap times) are often of interest in biomedical studies. For example, in a cancer study, the gap times from incidence-to-remission and remission-to-recurrence may be examined. Such ...
A shared random effects model for censored medical costs and mortality
(John Wiley & Sons, Ltd., 2006)
In this paper, we propose a model for medical costs recorded at regular time intervals, e.g. every month, as repeated measures in the presence of a terminating event, such as death. Prior models have related monthly medical ...
Semiparametric inferences for association with semi-competing risks data
(John Wiley & Sons, Ltd., 2005)
In many biomedical studies, it is of interest to assess dependence between bivariate failure time data. We focus here on a special type of such data, referred to as semi-competing risks data. In this article, we develop ...
Follicle-stimulating hormone signal transduction: Role of carbohydrate in aromatase induction in immature rat Sertoli cells
(Elsevier, 1991-08)
Receptor activated adenylate cyclase acts as a major transmembrane signalling system. It is widely accepted that upon binding to its receptor, follicle-stimulating hormone (FSH) activates the cAMP-dependent pathway which ...
Estimation for paired binomial data with application to radiation therapy
(John Wiley & Sons, Ltd., 2001-11-30)
We compare and contrast several different methods for estimating the effect of treatment when responses are paired binomial observations. The ratio of binomial probabilities is the parameter of interest, while the binomial ...
Optimal estimators for ambient air quality levels
(Elsevier, 1992)
Procedures to estimate missing data, determine extrema, and derive uncertainties for data collected in ambient air monitoring networks are presented. The optimal linear estimators used obtain unbiased, minimum variance ...
Generalizing the TITE-CRM to adapt for early- and late-onset toxicities
(John Wiley & Sons, Ltd., 2005)
Due to the staggered entry of subjects in phase I trials, some subjects will only be partially through the study when others are ready to be enrolled. Nonetheless, many phase I designs focus solely upon whether or not ...
Heat shock factor 1-deficient mice exhibit decreased recovery of hearing following noise overstimulation
(Wiley Subscription Services, Inc., A Wiley Company, 2005-08-15)
Heat shock proteins (Hsps) can enhance cell survival in response to stress. Heat shock factor 1 (Hsf1) is the major transcription factor that regulates stress-inducible Hsp expression. We previously demonstrated the ...