Now showing items 31-40 of 43
Bursting properties of units in cat globus pallidus and entopeduncular nucleus: the effect of excitotoxic striatal lesions
(Elsevier, 1991-05-24)
The bursting properties of units recorded in globus pallidus and entopeduncular nucleus were studied in awake cats sitting quietly before and after ipsilateral excitotoxic striatal lesions. A computerized statistical ...
Quantitative microdialysis determination of extracellular striatal dopamine concentration in male and female rats: effects of estrous cycle and gonadectomy
(Elsevier, 1994-10-24)
Sex differences in basal extracellular striatal dopamine concentrations in gonadectomized male and female rats have been reported previously. In the current experiment, estrous cycle-dependent variation, sex differences ...
The neural basis of drug craving: An incentive-sensitization theory of addiction
(Elsevier, 1993)
This paper presents a biopsychological theory of drug addiction, the `Incentive-Sensitization Theory'. The theory addresses three fundamental questions. The first is: why do addicts crave drugs? That is, what is the ...
Sustained behavioral recovery from unilateral nigrostriatal damage produced by the controlled release of dopamine from a silicone polymer pellet placed into the denervated striatum
(Elsevier, 1990-01-29)
This study was conducted to determine if the behavioral asymmetry associated with unilateral nigrostriatal dopamine (DA) depletion could be alleviated by placing a small DA-releasing silicone polymer matrix pellet into the ...
Amphetamine-Induced time-dependent sensitization of dopamine neurotransmission in the dorsal and ventral striatum: A microdialysis study in behaving rats
(Wiley Subscription Services, Inc., A Wiley Company, 1995-01)
The purpose of this study was to compare the effects of amphetamine exposure on subsequent amphetamine-induced changes in behavior and dopamine (DA) release in the dorsal and ventral striatum, as a function of time following ...
A multiwire microelectrode for single unit recording in deep brain structures
(Elsevier, 1990-05)
A method is described by which a single shaft multiwire microelectrode can be fabricated efficiently. The resulting electrode can be attached to a commercial microdrive and used for single neuronal unit recording from one ...
Relationship between asymmetries in striatal dopamine release and the direction of amphetamine-induced rotation during. The first week following a unilateral 6-OHDA lesion of the substantia nigra
(Wiley Subscription Services, Inc., A Wiley Company, 1994-05)
In animals with a large unilateral 6-hydroxydopamine (6-OHDA) lesion of the nigrostriatal dopamine (DA) system the traditional “rotational behavior model” states that amphetamine will induce circling behavior towards the ...
Where does damage lead to enhanced food aversion: the ventral pallidum/substantia innominata or lateral hypothalamus?
(Elsevier, 1993-10-08)
It is well known that lesions of the lateral hypothalamus (LH) produce aphagia. Several previous studies have reported that lateral hypothalamus damage produces food aversion in addition to aphagia. However, damage to other ...
A novel device for chronic intracranial drug delivery via microdialysis
(Elsevier, 1991-11)
A system is described for chronic intracranial drug administration in the rat using a modified in vivo microdialysis probe coupled to an Alzet model 2002 osmotic minipump. The results presented demonstrate that this system ...