Basolateral amygdaloid multi-unit neuronal correlates of discriminative avoidance learning in rabbits

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dc.contributor.author Maren, Stephen
dc.contributor.author Poremba, Amy
dc.contributor.author Gabriel, Michael
dc.date.accessioned 2007-10-02T15:15:00Z
dc.date.available 2007-10-02T15:15:00Z
dc.date.issued 1991-05-24
dc.identifier.citation Brain Research, 549(2):311-6. <http://hdl.handle.net/2027.42/56199> en_US
dc.identifier.uri http://hdl.handle.net/2027.42/56199
dc.identifier.uri http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1884224&dopt=citation en_US
dc.description.abstract Basolateral (BL) amygdaloid multi-unit activity was recorded as male albino rabbits learned to avoid a foot-shock unconditioned stimulus (US) by stepping in an activity wheel to an acoustic (pure tone) warning stimulus (CS+). A second tone (CS-) of different auditory frequency than the CS+ was presented in an irregular order on half of the conditioning trials but was never followed by the US. BL amygdaloid neurons developed, in the first session of conditioning, enhanced CS-elicited discharges relative to discharges recorded during pretraining with tones and noncontingent US presentations (excitatory plasticity), and greater discharges to the CS+ than to the CS- (discriminative plasticity). The discriminative plasticity attained maximal magnitude as the rabbits reached the asymptote of behavioral discrimination, and persisted during post-asymptotic training. Peak excitatory plasticity occurred in the session of the first significant behavioral discrimination and declined during the asymptotic and post-asymptotic stages of training. Similar patterns of excitatory and discriminative plasticity in structures directly interconnected with the BL nucleus (anterior cingulate cortex; medial dorsal thalamic nucleus) and effects of lesions suggest that the neurons in these areas participate in a circuit involved in mediation of avoidance learning. en_US
dc.format.extent 2084823 bytes
dc.format.mimetype application/pdf
dc.language.iso en_US en_US
dc.title Basolateral amygdaloid multi-unit neuronal correlates of discriminative avoidance learning in rabbits en_US
dc.type Article en_US
dc.subject.hlbsecondlevel Psychology
dc.subject.hlbtoplevel Social Sciences
dc.description.peerreviewed Peer Reviewed en_US
dc.contributor.affiliationother University of Illinois en_US
dc.contributor.affiliationumcampus Ann Arbor en_US
dc.identifier.pmid 1884224 en_US
dc.description.bitstreamurl http://deepblue.lib.umich.edu/bitstream/2027.42/56199/1/marenBRES91.pdf en_US
dc.owningcollname Psychology, Department of
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