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dc.contributor.authorJani, Sandeep M.en_US
dc.contributor.authorSmith, Dean E.en_US
dc.contributor.authorShare, Daviden_US
dc.contributor.authorKline-Rogers, Eva M.en_US
dc.contributor.authorKhanal, Sanjayaen_US
dc.contributor.authorO'Donnell, Michael J.en_US
dc.contributor.authorGardin, Juliusen_US
dc.contributor.authorMoscucci, Mauroen_US
dc.date.accessioned2007-12-04T18:27:30Z
dc.date.available2008-11-05T15:05:43Zen_US
dc.date.issued2007-10en_US
dc.identifier.citationJani, Sandeep M.; Smith, Dean E.; Share, David; Kline-Rogers, Eva; Khanal, Sanjaya; O'Donnell, Michael J.; Gardin, Julius; Moscucci, Mauro (2007). "Blood Transfusion and In-hospital Outcomes in Anemic Patients with Myocardial Infarction Undergoing Percutaneous Coronary Intervention Supported by an unrestricted grant from Blue Cross Blue Shield of Michigan, Detroit, Michigan, USA. ." Clinical Cardiology 30(S2): II-49-II-56. <http://hdl.handle.net/2027.42/57343>en_US
dc.identifier.issn0160-9289en_US
dc.identifier.issn1932-8737en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/57343
dc.description.abstractStudies have shown poor prognostic implications of anemia in patients with myocardial infarction (MI) and in patients undergoing percutaneous coronary intervention (PCI). The impact of blood transfusion in these populations remains controversial. The objective of this study was to examine the effect of transfusion on in-hospital mortality in anemic patients undergoing PCI for MI. Data from 67,051 PCIs (June 1, 1997 to January 31, 2004) were prospectively collected in a multicenter registry (Blue Cross Blue Shield of Michigan Cardiovascular Consortium). Of these, 4,623 patients who were classified as anemic according to the World Health Organization criteria underwent PCI within 7 days of presentation with acute MI. A propensity score for being transfused was estimated for each patient, and propensity matching and a prediction model for in-hospital death were developed. The average age was 67.8 years, 57.7% of patients were men, and 22.3% of patients received a transfusion during hospitalization. Transfused patients, compared to nontransfused patients, were more likely to be older, female, have lower preprocedure hemoglobin levels, more comorbidities, and a higher unadjusted in-hospital mortality rate (14.52% vs. 3.01%, p < 0.0001). After adjustment for comorbidities and propensity for transfusion, blood transfusion was associated with a higher risk of in-hospital mortality (adjusted odds ratio = 2.02, 95% confidence interval 1.47–2.79, p < 0.0001). In anemic patients undergoing PCI for MI, transfusion was associated with an increased crude and adjusted rate of in-hospital mortality. A randomized controlled trial is needed to determine the value of transfusion and the ideal transfusion criteria. Copyright © 2007 Wiley Periodicals, Inc.en_US
dc.format.extent263216 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWiley Periodicals, Inc.en_US
dc.subject.otherMedicine and Healthcareen_US
dc.subject.otherCardiovascular Diseaseen_US
dc.titleBlood Transfusion and In-hospital Outcomes in Anemic Patients with Myocardial Infarction Undergoing Percutaneous Coronary Intervention Supported by an unrestricted grant from Blue Cross Blue Shield of Michigan, Detroit, Michigan, USA.en_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelInternal Medicine and Specialitiesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDivision of Cardiology, University of Michigan Medical Centers, Ann Arboren_US
dc.contributor.affiliationumDivision of Cardiology, University of Michigan Medical Centers, Ann Arboren_US
dc.contributor.affiliationumDivision of Cardiology, University of Michigan Medical Centers, Ann Arboren_US
dc.contributor.affiliationumDivision of Cardiology, University of Michigan Medical Centers, Ann Arbor ; University Hospital, TC B1-226 1500 E. Medical Center Drive Ann Arbor, MI 48103-0311, USAen_US
dc.contributor.affiliationotherBlue Cross Blue Shield of Michiganen_US
dc.contributor.affiliationotherHenry Ford Hospital, Detroiten_US
dc.contributor.affiliationotherSt. Joseph Mercy Hospital, Ann Arboren_US
dc.contributor.affiliationotherSt. John's Hospital and Medical Center, Detroit, Michigan, USAen_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/57343/1/20236_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/clc.20236en_US
dc.identifier.sourceClinical Cardiologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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