Cross-shift peak expiratory flow changes are unassociated with respirable coal dust exposure among South African coal miners Human Subjects Declaration: All participants in this study gave written informed consent, participated voluntarily, and had the right to withdraw at any stage. Ethical approval was obtained from the Institutional Review Board of the University of Michigan and the Ethics Committee of University of KwaZulu-Natal.
dc.contributor.author | Naidoo, Rajen N. | en_US |
dc.contributor.author | Robins, Thomas G. | en_US |
dc.contributor.author | Becklake, Margaret | en_US |
dc.contributor.author | Seixas, Noah | en_US |
dc.contributor.author | Thompson, Mary Lou | en_US |
dc.date.accessioned | 2007-12-04T18:29:37Z | |
dc.date.available | 2009-01-07T20:01:16Z | en_US |
dc.date.issued | 2007-12 | en_US |
dc.identifier.citation | Naidoo, Rajen N.; Robins, Thomas G.; Becklake, Margaret; Seixas, Noah; Thompson, Mary Lou (2007). "Cross-shift peak expiratory flow changes are unassociated with respirable coal dust exposure among South African coal miners Human Subjects Declaration: All participants in this study gave written informed consent, participated voluntarily, and had the right to withdraw at any stage. Ethical approval was obtained from the Institutional Review Board of the University of Michigan and the Ethics Committee of University of KwaZulu-Natal. ." American Journal of Industrial Medicine 50(12): 992-998. <http://hdl.handle.net/2027.42/57355> | en_US |
dc.identifier.issn | 0271-3586 | en_US |
dc.identifier.issn | 1097-0274 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/57355 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=17918230&dopt=citation | en_US |
dc.description.abstract | Background The objectives of this study were to determine whether cross-shift changes in peak expiratory flow rate (PEFR) were related to respirable dust exposure in South African coalminers. Methods Fifty workers were randomly selected from a cohort of 684 miners from 3 bituminous coalmines in Mpumalanga, South Africa. Peak expiratory efforts were measured prior to the commencement of the shift, and at the end of the shift on at least two occasions separated by at least 2 weeks, with full shift personal dust sampling being conducted on each occasion for each participant. Interviews were conducted, work histories were obtained and cumulative exposure estimates were constructed. Regression models examined the associations of cross-shift changes in PEFR with current and cumulative exposure, controlling for shift, smoking and past history of tuberculosis. Results There were marginal differences in cross-shift PEFR (ranging from 0.1 to 2 L/min). Linear regression analyses showed no association between cross-shift change in PEFR and current or cumulative exposure. The specific shift worked by participants in the study showed no effect. Conclusions Our study showed no association between current respirable dust exposure and cross-shift changes in PEFR. There was a non-significant protective effect of cumulative dust exposure on the outcome, suggesting the presence of a “healthy worker survivor effect” in this data. Am. J. Ind. Med. 50:992–998, 2007. © 2007 Wiley-Liss, Inc. | en_US |
dc.format.extent | 116553 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Occupational Health and Environmental Toxicology | en_US |
dc.title | Cross-shift peak expiratory flow changes are unassociated with respirable coal dust exposure among South African coal miners Human Subjects Declaration: All participants in this study gave written informed consent, participated voluntarily, and had the right to withdraw at any stage. Ethical approval was obtained from the Institutional Review Board of the University of Michigan and the Ethics Committee of University of KwaZulu-Natal. | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Environmental Health Sciences, University of Michigan, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationother | Centre for Occupational and Environmental Health, University of KwaZulu-Natal, Durban, South Africa ; Centre for Occupational and Environmental Health, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Private Bag x7, Congella 4013, South Africa. | en_US |
dc.contributor.affiliationother | Department of Epidemiology, Biostatistics and Occupational Health, McGill University/Montreal Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, Montreal, Quebec, Canada | en_US |
dc.contributor.affiliationother | Department of Environmental Health, University of Washington, Seattle, Washington | en_US |
dc.contributor.affiliationother | Biostatistics Unit, Medical Research Council, Durban, South Africa | en_US |
dc.identifier.pmid | 17918230 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/57355/1/20513_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/ajim.20513 | en_US |
dc.identifier.source | American Journal of Industrial Medicine | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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