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Structural and mechanical evaluations of a topology optimized titanium interbody fusion cage fabricated by selective laser melting process

dc.contributor.authorLin, Chia-Yingen_US
dc.contributor.authorWirtz, Tobiasen_US
dc.contributor.authorLaMarca, Franken_US
dc.contributor.authorHollister, Scott J.en_US
dc.date.accessioned2007-12-04T18:37:01Z
dc.date.available2008-11-05T15:05:43Zen_US
dc.date.issued2007-11en_US
dc.identifier.citationLin, Chia-Ying; Wirtz, Tobias; LaMarca, Frank; Hollister, Scott J. (2007). "Structural and mechanical evaluations of a topology optimized titanium interbody fusion cage fabricated by selective laser melting process." Journal of Biomedical Materials Research Part A 83A(2): 272-279. <http://hdl.handle.net/2027.42/57400>en_US
dc.identifier.issn1549-3296en_US
dc.identifier.issn1552-4965en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/57400
dc.description.abstractA topology optimized lumbar interbody fusion cage was made of Ti-Al6-V4 alloy by the rapid prototyping process of selective laser melting (SLM) to reproduce designed microstructure features. Radiographic characterizations and the mechanical properties were investigated to determine how the structural characteristics of the fabricated cage were reproduced from design characteristics using micro-computed tomography scanning. The mechanical modulus of the designed cage was also measured to compare with tantalum, a widely used porous metal. The designed microstructures can be clearly seen in the micrographs of the micro-CT and scanning electron microscopy examinations, showing the SLM process can reproduce intricate microscopic features from the original designs. No imaging artifacts from micro-CT were found. The average compressive modulus of the tested caged was 2.97 ± 0.90 GPa, which is comparable with the reported porous tantalum modulus of 3 GPa and falls between that of cortical bone (15 GPa) and trabecular bone (0.1–0.5 GPa). The new porous Ti-6Al-4V optimal-structure cage fabricated by SLM process gave consistent mechanical properties without artifactual distortion in the imaging modalities and thus it can be a promising alternative as a porous implant for spine fusion. © 2007 Wiley Periodicals, Inc. J Biomed Mater Res 2007en_US
dc.format.extent396172 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWiley Subscription Services, Inc., A Wiley Companyen_US
dc.subject.otherChemistryen_US
dc.subject.otherPolymer and Materials Scienceen_US
dc.titleStructural and mechanical evaluations of a topology optimized titanium interbody fusion cage fabricated by selective laser melting processen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelBiomedical Engineeringen_US
dc.subject.hlbtoplevelEngineeringen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumSpine Research Laboratory, Department of Neurosurgery, The University of Michigan, Ann Arbor, Michigan ; Scaffold Tissue Engineering Group, The University of Michigan, Ann Arbor, Michigan ; Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan ; Spine Research Laboratory, Department of Neurosurgery, The University of Michigan, Ann Arbor, Michiganen_US
dc.contributor.affiliationumSpine Research Laboratory, Department of Neurosurgery, The University of Michigan, Ann Arbor, Michiganen_US
dc.contributor.affiliationumScaffold Tissue Engineering Group, The University of Michigan, Ann Arbor, Michigan ; Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan ; Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan ; Department of Surgery, University of Michigan, Ann Arbor, Michiganen_US
dc.contributor.affiliationotherFraunhofer Institute of Laser Technology, Aachen, Germanyen_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/57400/1/31231_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/jbm.a.31231en_US
dc.identifier.sourceJournal of Biomedical Materials Research Part Aen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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