Now showing items 1-10 of 17
Induction of glutathione S -transferase-Π in Barrett's metaplasia and Barrett's adenocarcinoma cell lines
(John Wiley & Sons, Inc., 1999-02)
Barrett's metaplasia consists of columnar epithelium that replaces the normal esophageal mucosa in patients with chronic gastroesophageal reflux. Because intestinal-type Barrett's metaplasia is the major risk factor for ...
Concurrent cisplatin, paclitaxel, and radiotherapy as preoperative treatment for patients with locoregional esophageal carcinoma
(Wiley Subscription Services, Inc., A Wiley Company, 2003-11-15)
BACKGROUND A Phase II trial was conducted at the University of Michigan to determine the efficacy of a preoperative regimen of concurrent cisplatin, paclitaxel, and radiation for patients with locoregional esophageal ...
Three dimensional CT of central lung tumors
(Elsevier, 1990)
Three-dimensional computed tomography (CT) reconstructions and conventional CT were compared with surgical /pathological findings in seven patients with central lung tumors, in order to assess accuracy in predicting the ...
Transhiatal esophagectomy for distal and cardia cancers: implications of a positive gastric margin.
(Annals of Thoracic Surgery, 2007-06)
BACKGROUND: A common operation for cancer of the esophagus and cardia consists of transhiatal esophagectomy, proximal gastrectomy, and a cervical esophagogastric anastomosis. The oncologic adequacy of dividing the stomach ...
Distal chromosome 17q loss in Barrett's esophageal and gastric cardia adenocarcinomas: Implications for tumorigenesis
(John Wiley & Sons, Inc., 1998-08)
The molecular genetic mechanisms underlying esophageal cancer are poorly understood. However, a novel gene that may be involved in esophageal carcinogenesis was recently localized by others to distal 17q by linkage analysis ...
Reduced selenium-binding protein 1 expression is associated with poor outcome in lung adenocarcinomas
(John Wiley & Sons, Ltd., 2004-03)
The effects of selenium, an essential nutrient with anti-carcinogenic properties, are mediated by selenium-binding proteins. The protein expression status of human selenium-binding protein 1 (SBP1) in human tumours and the ...
Finite proliferative lifespan in vitro of a human breast cancer cell strain isolated from a metastatic lymph node
(Kluwer Academic Publishers; Springer Science+Business Media, 1993-01)
We recently described culture conditions that allow proliferation of metastatic human breast cancer cells from biopsy specimens of certain patient samples. These conditions resulted in the development of an immortalized ...
Molecular characterization of FRAXB and comparative common fragile site instability in cancer cells
(John Wiley & Sons, Inc., 2002-01)
The common fragile site, FRA3B, has been shown to be a site of frequent homozygous deletions in some cancers, resulting in loss of expression of the associated FHIT gene. It has been proposed that FHIT is a tumor ...
Multiple forms of genetic instability within a 2-Mb chromosomal segment of 3q26.3–q27 are associated with development of esophageal adenocarcinoma
(Wiley Subscription Services, Inc., A Wiley Company, 2006-04)
Gene amplification is one of the mechanisms to activate oncogenes in many cancers, including esophageal adenocarcinoma (EA). In the present study, we used two-dimensional restriction landmark genome scanning to clone a ...