Electrodeless direct current dielectrophoresis using reconfigurable field-shaping oil barriers
dc.contributor.author | Thwar, Prasanna K. | en_US |
dc.contributor.author | Linderman, Jennifer J. | en_US |
dc.contributor.author | Burns, Mark A. | en_US |
dc.date.accessioned | 2008-01-04T20:07:44Z | |
dc.date.available | 2009-01-07T20:01:16Z | en_US |
dc.date.issued | 2007-12 | en_US |
dc.identifier.citation | Thwar, Prasanna K.; Linderman, Jennifer J.; Burns, Mark A. (2007). "Electrodeless direct current dielectrophoresis using reconfigurable field-shaping oil barriers." Electrophoresis 28(24): 4572-4581. <http://hdl.handle.net/2027.42/57515> | en_US |
dc.identifier.issn | 0173-0835 | en_US |
dc.identifier.issn | 1522-2683 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/57515 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=18072223&dopt=citation | en_US |
dc.description.abstract | We demonstrate dielectrophoretic (DEP) potential wells using pairs of insulating oil menisci to shape the DC electric field. These oil menisci are arranged in a configuration similar to the quadrupolar electrodes, typically used in DEP, and are shown to produce similar field gradients. While the one-pair well produces a focusing effect on particles in flow, the two-pair well results in creating spatial traps against crossflows. Uncharged polystyrene particles were used to map the DEP force fields and the experimental observations were compared against the field profiles obtained by numerically solving Maxwell's equations. We demonstrate trapping of a single particle due to negative DEP against a pressure-driven crossflow. This can be easily extended to trap and hold cells and other objects against flow for a longer time. We also show the results of particle trapping experiments performed to observe the effect of adjusting the oil menisci and the gap between two pairs of menisci in a four-menisci configuration on the nature of the DEP well formed at the center. A design parameter, Θ, capturing the dimensions of the DEP energy well, is defined and simulations exploring the effects of different geometric features on Θ are presented. | en_US |
dc.format.extent | 593730 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | WILEY-VCH Verlag | en_US |
dc.subject.other | Chemistry | en_US |
dc.subject.other | Biochemistry and Biotechnology | en_US |
dc.title | Electrodeless direct current dielectrophoresis using reconfigurable field-shaping oil barriers | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Chemical Engineering | en_US |
dc.subject.hlbsecondlevel | Chemistry | en_US |
dc.subject.hlbsecondlevel | Materials Science and Engineering | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Engineering | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA ; 615 Davis Drive, Suite 800, Morrisville, NC 27560, USA Fax: +1-919-287-9011 | en_US |
dc.contributor.affiliationum | Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA ; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA ; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA | en_US |
dc.identifier.pmid | 18072223 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/57515/1/4572_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/elps.200700373 | en_US |
dc.identifier.source | Electrophoresis | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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