Versatile Preparation of Fluorescent Particles Based on Polyphosphazenes: From Micro- to Nanoscale

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dc.contributor.author Zhang, Jianxiang en_US
dc.contributor.author Qiu, Liyan en_US
dc.contributor.author Li, Xiaodong en_US
dc.contributor.author Jin, Yi en_US
dc.contributor.author Zhu, Kangjie en_US
dc.date.accessioned 2008-01-04T20:13:07Z
dc.date.available 2009-01-07T20:01:16Z en_US
dc.date.issued 2007-12-03 en_US
dc.identifier.citation Zhang, Jianxiang; Qiu, Liyan; Li, Xiaodong; Jin, Yi; Zhu, Kangjie (2007). "Versatile Preparation of Fluorescent Particles Based on Polyphosphazenes: From Micro- to Nanoscale." Small 3(12): 2081-2093. <http://hdl.handle.net/2027.42/57545> en_US
dc.identifier.issn 1613-6810 en_US
dc.identifier.issn 1613-6829 en_US
dc.identifier.uri http://hdl.handle.net/2027.42/57545
dc.identifier.uri http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=18034440&dopt=citation en_US
dc.description.abstract A series of intrinsically fluorescent hydrophobic and amphiphilic polyphosphazenes with ethyl tryptophan (EtTrp) and poly(N-isopropylacrylamide) (PNIPAAm) or poly(ethylene glycol) (PEG) as hydrophobic and hydrophilic segments, respectively, are synthesized. Depending on polymer composition and preparation procedure, particles with diameters ranging from micro- to nanoscale can be prepared successfully, which might be used as a visible tracer, both in 14vitro or in 14vivo, in drug- or gene-delivery systems, as well as in other biomedical studies such as diagnostic medicine and brain research. Most importantly, in combination with the flexible synthesis and versatile modification of polyphosphazene, this method provides a general protocol to engineer a broad range of fluorescent particles with different properties based on diverse polymers. en_US
dc.format.extent 1733445 bytes
dc.format.extent 3118 bytes
dc.format.mimetype application/pdf
dc.format.mimetype text/plain
dc.publisher WILEY-VCH Verlag en_US
dc.subject.other Polymers and Materials Science en_US
dc.subject.other General Materials Science en_US
dc.title Versatile Preparation of Fluorescent Particles Based on Polyphosphazenes: From Micro- to Nanoscale en_US
dc.rights.robots IndexNoFollow en_US
dc.subject.hlbsecondlevel Materials Science and Engineering en_US
dc.subject.hlbsecondlevel Physics en_US
dc.subject.hlbtoplevel Engineering en_US
dc.subject.hlbtoplevel Science en_US
dc.description.peerreviewed Peer Reviewed en_US
dc.contributor.affiliationum Key Laboratory of Macromolecule Synthesis and Functionalization, Ministry of Education, Institute of Polymer Science, Zhejiang University, Hangzhou 310027, P.R. China, Fax: (+86) 571-879-517-73 ; Present address: Department of Biologic and Materials Sciences, University of Michigan, 1011 N University Ave, Ann Arbor, MI 48109, USA ; en_US
dc.contributor.affiliationum College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310068, P.R. China, Fax: (+86) 571-882-084-35 ; en_US
dc.contributor.affiliationother Affiliated Stomatology Hospital, College of Medicine, Zhejiang University, Hangzhou 310068, P.R. China en_US
dc.contributor.affiliationother College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310068, P.R. China, Fax: (+86) 571-882-084-35 en_US
dc.contributor.affiliationother Key Laboratory of Macromolecule Synthesis and Functionalization, Ministry of Education, Institute of Polymer Science, Zhejiang University, Hangzhou 310027, P.R. China, Fax: (+86) 571-879-517-73 en_US
dc.identifier.pmid 18034440 en_US
dc.description.bitstreamurl http://deepblue.lib.umich.edu/bitstream/2027.42/57545/1/2081_ftp.pdf en_US
dc.identifier.doi http://dx.doi.org/10.1002/smll.200700069 en_US
dc.identifier.source Small en_US
dc.owningcollname Interdisciplinary and Peer-Reviewed
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