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Versatile Preparation of Fluorescent Particles Based on Polyphosphazenes: From Micro- to Nanoscale
dc.contributor.authorZhang, Jianxiangen_US
dc.contributor.authorQiu, Liyanen_US
dc.contributor.authorLi, Xiaodongen_US
dc.contributor.authorJin, Yien_US
dc.contributor.authorZhu, Kangjieen_US
dc.date.accessioned2008-01-04T20:13:07Z
dc.date.available2009-01-07T20:01:16Zen_US
dc.date.issued2007-12-03en_US
dc.identifier.citationZhang, Jianxiang; Qiu, Liyan; Li, Xiaodong; Jin, Yi; Zhu, Kangjie (2007). "Versatile Preparation of Fluorescent Particles Based on Polyphosphazenes: From Micro- to Nanoscale." Small 3(12): 2081-2093. <http://hdl.handle.net/2027.42/57545>en_US
dc.identifier.issn1613-6810en_US
dc.identifier.issn1613-6829en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/57545
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=18034440&dopt=citationen_US
dc.description.abstractA series of intrinsically fluorescent hydrophobic and amphiphilic polyphosphazenes with ethyl tryptophan (EtTrp) and poly(N-isopropylacrylamide) (PNIPAAm) or poly(ethylene glycol) (PEG) as hydrophobic and hydrophilic segments, respectively, are synthesized. Depending on polymer composition and preparation procedure, particles with diameters ranging from micro- to nanoscale can be prepared successfully, which might be used as a visible tracer, both in 14vitro or in 14vivo, in drug- or gene-delivery systems, as well as in other biomedical studies such as diagnostic medicine and brain research. Most importantly, in combination with the flexible synthesis and versatile modification of polyphosphazene, this method provides a general protocol to engineer a broad range of fluorescent particles with different properties based on diverse polymers.en_US
dc.format.extent1733445 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWILEY-VCH Verlagen_US
dc.subject.otherPolymers and Materials Scienceen_US
dc.subject.otherGeneral Materials Scienceen_US
dc.titleVersatile Preparation of Fluorescent Particles Based on Polyphosphazenes: From Micro- to Nanoscaleen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMaterials Science and Engineeringen_US
dc.subject.hlbsecondlevelPhysicsen_US
dc.subject.hlbtoplevelEngineeringen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumKey Laboratory of Macromolecule Synthesis and Functionalization, Ministry of Education, Institute of Polymer Science, Zhejiang University, Hangzhou 310027, P.R. China, Fax: (+86) 571-879-517-73 ; Present address: Department of Biologic and Materials Sciences, University of Michigan, 1011 N University Ave, Ann Arbor, MI 48109, USA ;en_US
dc.contributor.affiliationumCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310068, P.R. China, Fax: (+86) 571-882-084-35 ;en_US
dc.contributor.affiliationotherAffiliated Stomatology Hospital, College of Medicine, Zhejiang University, Hangzhou 310068, P.R. Chinaen_US
dc.contributor.affiliationotherCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310068, P.R. China, Fax: (+86) 571-882-084-35en_US
dc.contributor.affiliationotherKey Laboratory of Macromolecule Synthesis and Functionalization, Ministry of Education, Institute of Polymer Science, Zhejiang University, Hangzhou 310027, P.R. China, Fax: (+86) 571-879-517-73en_US
dc.identifier.pmid18034440en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/57545/1/2081_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/smll.200700069en_US
dc.identifier.sourceSmallen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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