Now showing items 1-10 of 46
Increased immunoglobulin response to [gamma]-interferon by lymphocytes from patients with systemic lupus erythematosus
(Elsevier, 1988-01)
The factors responsible for abnormal B-cell activation in systemic lupus erythematosus (SLE) are incompletely understood. This study tested the hypothesis that the abnormal B-cell activation observed in human SLE may be ...
Bim--Bcl-2 Homology 2 Mimetic Therapy in Effective at Suppressing Inflammatory Arthritis Through the Activation of Myeloid Cell Apoptosis
(American College of Rheumatology, 2010-02)
Objective: Rheumatoid arthritis (RA) is a destructive autoimmune disease characterized by an increased inflammation in the joint. Therapies that activate the apoptotic cascade may have potential for use in RA; however, few ...
Placental histology and neutrophil extracellular traps in lupus and preeclampsia pregnancies.
(BMJ Publishing Group, 2016)
Atrioventricular conduction in children of women with systemic lupus erythematosus
(Elsevier, 1993-01-01)
The neonatal lupus syndrome consists of transient cutaneous lupus lesions or permanent congenital complete heart block (or hepatic fibrosis), or both, in infants born to mothers with systemic lupus erythematosus (SLE). The ...
Mercury Exposure and Antinuclear Antibodies among Females of Reproductive Age in the United States: NHANES
(National Institute of Environmental Health Sciences, 2015-02)
Background: Immune dysregulation associated with mercury has been suggested, though data in the general population are lacking. Chronic exposure to low levels of methylmercury (organic) and inorganic mercury is common, ...
CD4+ cells treated with DNA methylation inhibitors induce autologous B cell differentiation
(Elsevier, 1990-06)
The DNA methylation inhibitor 5-azacytidine induces autoreactivity in cloned CD4+ T cells, but the functional consequences of this response are unknown. We now report that CD4+ T cells treated with 5-azacytidine respond ...
The apoptotic ligands TRAIL, TWEAK, and Fas ligand mediate monocyte death induced by autologous lupus T cells.
(The American Association of Immunologists, 2002)