Now showing items 1-10 of 13
Effect of an inhibitor of DNA methylation on T cells. II. 5-azacytidine induces self-reactivity in antigen-specific T4+ cells
(Elsevier, 1986-12)
During T-cell maturation, thymocytes interact with thymic stromal major histocompatibility complex (MHC) determinants and thymic hormones, and proliferate, apparently in response to MHC gene products, in the absence of ...
The acute inflammatory reaction
(Elsevier, 1989-10)
A major theme in current developments in this field has been the realization that the target tissue, in particular the endothelium, has an active role in initiating and participating in inflammatory reactions and is not a ...
Evidence that macrophages are programmed to die after activating autologous, cloned, antigen-specific, CD4 + T cells
(WILEY-VCH Verlag GmbH, 1993-07)
The bone marrow produces large numbers of monocytes daily, but the mechanisms balancing production and elimination are unknown. In this report we demonstrate that macrophages (Mφ) undergo apoptosis after activating autologous ...
Factors Affecting Students' Use of MEDLINE
(Elsevier, 1993-12)
MEDLINE search transcripts by a class of third-year medical students were analyzed. The 184 students were divided into three groups according to their search experience in terms of the number of sessions logged at the time ...
Risk factors for disability among U.S. adults with arthritis
(Elsevier, 1991)
This article studies risk factors for physical and social disability among U.S. adults ages 55+ who have arthritis, compared to non-arthritis persons of those ages. The dependent variables refer to difficulties in walking, ...
Decay-accelerating factor is a component of subendothelial extracellular matrix in vitro , and is augmented by activation of endothelial protein kinase C
(WILEY-VCH Verlag GmbH, 1998-03)
The vasculature is protected from complement activation by regulatory molecules expressed on endothelial cells. However, complement fixation also occurs on subendothelial extracellular matrix (ECM) in vitro, and is ...
Fas ligation triggers apoptosis in macrophages but not endothelial cells
(WILEY-VCH Verlag GmbH, 1994-11)
The reticuloendothelial system includes macrophages and endothelial cells. These cells are produced and destroyed in vivo with a precision that implies the existence of homeostatic mechanisms. The stimuli for endothelial ...
Activation of human T cell clones through the UM4D4/CDw60 surface antigen
(Elsevier, 1990-07)
UM4D4 is a recently defined antigen that is expressed on ~25% of peripheral blood T cells, but on the majority of T cells in inflammatory synovial fluid. Anti-UM4D4 activates peripheral blood T cells in the presence of ...
The Human 4F2 Antigen: Evidence for Cryptic and Noncryptic Epitopes and for a Role of 4F2 in Human T Lymphocyte Activation
(Elsevier, 1994-04-01)
T lymphocyte activation can be triggered through multiple distinct, but functionally related, pathways. Murine monoclonal antibodies (mAbs) have been used to characterize the surface components of several of these pathways, ...